5EKW
A. thaliana IGPD2 in complex with the racemate of the triazole-phosphonate inhibitor, C348
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Imidazoleglycerol-phosphate dehydratase 2, chloroplastic | polymer | 205 | 22391.1 | 1 | UniProt (O23346) Pfam (PF00475) In PDB | Arabidopsis thaliana (Mouse-ear cress) | IGPD 2,Protein HISTIDINE BIOSYNTHESIS 5B, Imidazoleglycerolphosphate-dehydratase isoform 2, IGPD2 |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | [(2S)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid | non-polymer | 207.1 | 1 | Chemie (5DL) | |||
| 4 | A | [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid | non-polymer | 207.1 | 1 | Chemie (5LD) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 7 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A: 4 - 207 (UniProt: O23346)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22391.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1176.3 | |
| All* | Total formula weight | 23567.4 |
