5EGQ

Structure of tetrameric rat phenylalanine hydroxylase mutant R270K, residues 25-453

Summary for 5EGQ

Entry DOI	10.2210/pdb5egq/pdb
Descriptor	Phenylalanine-4-hydroxylase, SULFATE ION (3 entities in total)
Functional Keywords	hydroxylase, phenylketonuria, pku mutation, allostery, act domain, oxidoreductase
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	4
Total formula weight	208006.64
Authors	Taylor, A.B.,Khan, C.A.,Fitzpatrick, P.F. (deposition date: 2015-10-27, release date: 2016-05-18, Last modification date: 2023-09-27)
Primary citation	Meisburger, S.P.,Taylor, A.B.,Khan, C.A.,Zhang, S.,Fitzpatrick, P.F.,Ando, N. Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering. J.Am.Chem.Soc., 138:6506-6516, 2016 Cited by PubMed: 27145334 DOI: 10.1021/jacs.6b01563 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation