5KSI
 
 | | Crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-Bisphosphoglycerate | | 分子名称: | (2R)-2,3-diphosphoglyceric acid, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, ... | | 著者 | Ahmed, M.H, Safo, M.K, Xia, Y. | | 登録日 | 2016-07-08 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
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5HJ0
 | | Crystal Structure of Mis18 'Yippee-like' Domain | | 分子名称: | Kinetochore protein mis18, ZINC ION | | 著者 | Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A. | | 登録日 | 2016-01-12 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization.
Embo Rep., 17, 2016
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6AYN
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6AZK
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6AXP
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6AU5
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6AZL
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6W1S
 | | Atomic model of the mammalian Mediator complex | | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | | 著者 | Zhao, H, Young, N, Asturias, F. | | 登録日 | 2020-03-04 | | 公開日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Cell, 178, 2019
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4QMD
 | | Crystal structure of human envoplakin plakin repeat domain | | 分子名称: | Envoplakin | | 著者 | Mohammed, F, Al-Jassar, C, White, S.A, Fogl, C, Jeeves, M, Knowles, T.J, Odinstova, E, Rodriguez-Zamora, P, Overduin, M, Chidgey, M. | | 登録日 | 2014-06-16 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.
Nat Commun, 7, 2016
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3V5M
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3V50
 | | Complex of SHV S130G mutant beta-lactamase complexed to SA2-13 | | 分子名称: | (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, Beta-lactamase, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | | 著者 | Wei, K, van den Akker, F. | | 登録日 | 2011-12-15 | | 公開日 | 2012-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The importance of the trans-enamine intermediate as a beta-lactamase inhibition strategy probed in inhibitor-resistant SHV beta-lactamase variants.
Chemmedchem, 7, 2012
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4H62
 | | Structure of the Saccharomyces cerevisiae Mediator subcomplex Med17C/Med11C/Med22C | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ... | | 著者 | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | | 登録日 | 2012-09-19 | | 公開日 | 2012-10-31 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the Mediator head module.
Nature, 492, 2012
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6XP5
 | | Head-Middle module of Mediator | | 分子名称: | HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ... | | 著者 | Zhang, H.Q, Chen, D.C, Kornberg, R.D. | | 登録日 | 2020-07-08 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mediator structure and conformation change.
Mol.Cell, 81, 2021
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4GWQ
 | | Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ... | | 著者 | Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D. | | 登録日 | 2012-09-03 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2HZS
 | | Structure of the Mediator head submodule Med8C/18/20 | | 分子名称: | RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8 | | 著者 | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | | 登録日 | 2006-08-09 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
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2HZM
 | | Structure of the Mediator head subcomplex Med18/20 | | 分子名称: | PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20 | | 著者 | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | | 登録日 | 2006-08-09 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
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2P4H
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2PQ6
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6H02
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2ACV
 | | Crystal Structure of Medicago truncatula UGT71G1 | | 分子名称: | URIDINE-5'-DIPHOSPHATE, triterpene UDP-glucosyl transferase UGT71G1 | | 著者 | Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X. | | 登録日 | 2005-07-19 | | 公開日 | 2005-11-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula.
Plant Cell, 17, 2005
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1YKE
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1YKH
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2ACW
 | | Crystal Structure of Medicago truncatula UGT71G1 complexed with UDP-glucose | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, triterpene UDP-glucosyl transferase UGT71G1 | | 著者 | Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X. | | 登録日 | 2005-07-19 | | 公開日 | 2005-11-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula.
Plant Cell, 17, 2005
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1I76
 | | COMPLEX OF 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID (D-TIC DERIVATIVE) WITH T CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | 分子名称: | 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, CALCIUM ION, NEUTROPHIL COLLAGENASE, ... | | 著者 | Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A. | | 登録日 | 2001-03-08 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000
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1I73
 | | COMPLEX OF PRO-LEU-L-TRP PHOSPHONATE WITH THE CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | 分子名称: | CALCIUM ION, NEUTROPHIL COLLAGENASE, THREE RESIDUE PEPTIDE INHIBITOR, ... | | 著者 | Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A. | | 登録日 | 2001-03-07 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000
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