4QMD
Crystal structure of human envoplakin plakin repeat domain
Summary for 4QMD
Entry DOI | 10.2210/pdb4qmd/pdb |
Descriptor | Envoplakin (2 entities in total) |
Functional Keywords | envoplakin, periplakin, plakin protein, plakin repeat domain, cornified envelope, epidermal permeability barrier, keratinocyte, terminal differentiation, intermediate filament, vimentin, cytoskeleton, cell junction, desmosome, paraneoplastic pemphigus, cell adhesion |
Biological source | Homo sapiens (human) |
Cellular location | Cell junction, desmosome: Q92817 |
Total number of polymer chains | 2 |
Total formula weight | 42480.75 |
Authors | Mohammed, F.,Al-Jassar, C.,White, S.A.,Fogl, C.,Jeeves, M.,Knowles, T.J.,Odinstova, E.,Rodriguez-Zamora, P.,Overduin, M.,Chidgey, M. (deposition date: 2014-06-16, release date: 2015-07-29, Last modification date: 2024-02-28) |
Primary citation | Fogl, C.,Mohammed, F.,Al-Jassar, C.,Jeeves, M.,Knowles, T.J.,Rodriguez-Zamora, P.,White, S.A.,Odintsova, E.,Overduin, M.,Chidgey, M. Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin. Nat Commun, 7:10827-10827, 2016 Cited by PubMed: 26935805DOI: 10.1038/ncomms10827 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.601 Å) |
Structure validation
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