8TRH

The IDRc bound human core Mediator complex

Summary for 8TRH

Entry DOI	10.2210/pdb8trh/pdb
EMDB information	41580
Descriptor	Mediator of RNA polymerase II transcription subunit 27, Mediator of RNA polymerase II transcription subunit 7, Mediator of RNA polymerase II transcription subunit 8, ... (27 entities in total)
Functional Keywords	transcription, mediator.
Biological source	Homo sapiens (human) More
Total number of polymer chains	26
Total formula weight	1477913.65
Authors	Chen, S.F.,Chao, T.C.,Kim, H.J.,Tang, H.C.,Khadka, S.,Li, T.,Murakami, K.,Boyer, T.G.,Tsai, K.L. (deposition date: 2023-08-09, release date: 2024-10-09)
Primary citation	Chao, T.C.,Chen, S.F.,Kim, H.J.,Tang, H.C.,Tseng, H.C.,Xu, A.,Palao 3rd, L.,Khadka, S.,Li, T.,Huang, M.F.,Lee, D.F.,Murakami, K.,Boyer, T.G.,Tsai, K.L. Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol.Cell, 2024 Cited by PubMed: 39321804 DOI: 10.1016/j.molcel.2024.09.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation