6AYN

Structure of cetuximab with aminoheptanoic acid-linked N-(3-aminopropyl)-L-arginine meditope variant

Summary for 6AYN

• Entry DOI: 10.2210/pdb6ayn/pdb
• Related: 5id0 6au5
• Descriptor: Cetuximab Fab light chain, Cetuximab Fab heavy chain, Cyclic meditope, ... (4 entities in total)
• Functional Keywords: antibody, anti-egfr, immune system
• Biological source: Mus musculus (Mouse); More
• Cellular location: Secreted : P01834
• Total number of polymer chains: 6
• Total formula weight: 96925.90

Authors

Bzymek, K.P.,Williams, J.C. (deposition date: 2017-09-08, release date: 2017-12-13, Last modification date: 2023-11-15)

• Primary citation: Bzymek, K.P.,Ma, Y.,Avery, K.N.,Horne, D.A.,Williams, J.C.; Meditope-Fab interaction: threading the hole.; Acta Crystallogr F Struct Biol Commun, 73:688-694, 2017; PubMed: 29199990; DOI: 10.1107/S2053230X17016272

Experimental method

X-RAY DIFFRACTION (2.48 Å)