6AYN

Structure of cetuximab with aminoheptanoic acid-linked N-(3-aminopropyl)-L-arginine meditope variant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0003823	molecular_function	antigen binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006955	biological_process	immune response
A	0016064	biological_process	immunoglobulin mediated immune response
A	0019814	cellular_component	immunoglobulin complex
A	0050853	biological_process	B cell receptor signaling pathway
A	0070062	cellular_component	extracellular exosome
A	0071735	cellular_component	IgG immunoglobulin complex
A	0071738	cellular_component	IgD immunoglobulin complex
A	0071742	cellular_component	IgE immunoglobulin complex
A	0071745	cellular_component	IgA immunoglobulin complex
A	0071753	cellular_component	IgM immunoglobulin complex
A	0072562	cellular_component	blood microparticle
C	0002250	biological_process	adaptive immune response
C	0003823	molecular_function	antigen binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005886	cellular_component	plasma membrane
C	0006955	biological_process	immune response
C	0016064	biological_process	immunoglobulin mediated immune response
C	0019814	cellular_component	immunoglobulin complex
C	0050853	biological_process	B cell receptor signaling pathway
C	0070062	cellular_component	extracellular exosome
C	0071735	cellular_component	IgG immunoglobulin complex
C	0071738	cellular_component	IgD immunoglobulin complex
C	0071742	cellular_component	IgE immunoglobulin complex
C	0071745	cellular_component	IgA immunoglobulin complex
C	0071753	cellular_component	IgM immunoglobulin complex
C	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
B	TYR200-HIS206
A	TYR192-HIS198

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