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3UEG
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BU of 3ueg by Molmil
Crystal structure of human Survivin K62A mutant
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, TETRAETHYLENE GLYCOL, ...
著者Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
登録日2011-10-30
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol.Biol.Cell, 23, 2012
3UIK
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BU of 3uik by Molmil
crystal structure of human Survivin mutant K62Y/H80W in complex with H3(1-10) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
3UEI
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BU of 3uei by Molmil
Crystal structure of human Survivin E65A mutant
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION
著者Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
登録日2011-10-30
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol Biol Cell, 23, 2012
6O22
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BU of 6o22 by Molmil
Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.
分子名称: Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ...
著者Danilenko, N, Carlomagno, T, Kirkpatrick, J.P.
登録日2019-02-22
公開日2019-07-31
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Histone chaperone exploits intrinsic disorder to switch acetylation specificity.
Nat Commun, 10, 2019
7V1K
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BU of 7v1k by Molmil
Apo structure of sNASP core
分子名称: Isoform 2 of Nuclear autoantigenic sperm protein
著者Bao, H, Huang, H.
登録日2021-08-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
3KMT
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BU of 3kmt by Molmil
Crystal structure of vSET/SAH/H3 ternary complex
分子名称: A612L protein, Histone H3, S-ADENOSYL-L-HOMOCYSTEINE
著者Wei, H, Zhou, M.M.
登録日2009-11-11
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Dimerization of a viral SET protein endows its function.
Proc.Natl.Acad.Sci.USA, 107, 2010
7OKP
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BU of 7okp by Molmil
Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Histone H3.3, Histone-arginine methyltransferase CARM1, ...
著者Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J.
登録日2021-05-18
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors.
Chembiochem, 22, 2021
7OS4
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Crystal structure of mouse CARM1 in complex with histone H3_13-31 K18
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Histone H3.1, Histone-arginine methyltransferase CARM1
著者Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J.
登録日2021-06-07
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors.
Chembiochem, 22, 2021
8DYO
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BU of 8dyo by Molmil
Cryo-EM structure of Importin-4 bound to RanGTP
分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-4, ...
著者Bernardes, N.E, Fung, H.Y.J, Li, Y, Chen, Z, Chook, Y.M.
登録日2022-08-04
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
5Z23
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BU of 5z23 by Molmil
Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Arimura, Y, Tachiwana, H, Takagi, H.
登録日2017-12-28
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
5ZBX
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BU of 5zbx by Molmil
The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D)
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Arimura, Y, Takagi, H, Kurumizaka, H.
登録日2018-02-13
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism.
Nat Commun, 10, 2019
7LBQ
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BU of 7lbq by Molmil
Crystal structure of human Survivin bound to histone H3 T3phK4me2 peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3 T3phK4me2 peptide
著者Niedzialkowska, E, Minor, W, Stukenberg, P.T.
登録日2021-01-08
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization.
Mol.Biol.Cell, 33, 2022
7LBK
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BU of 7lbk by Molmil
Crystal structure of human Survivin bound to histone H3 T3phK4me3 peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3 T3phK4me3 peptide
著者Niedzialkowska, E, Minor, W, Stukenberg, P.T.
登録日2021-01-08
公開日2022-01-12
最終更新日2022-08-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization.
Mol.Biol.Cell, 33, 2022
7LBO
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BU of 7lbo by Molmil
Crystal structure of human Survivin bound to histone H3 T3phK4me1 peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3 T3phK4me1 peptide
著者Niedzialkowska, E, Minor, W, Stukenberg, P.T.
登録日2021-01-08
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization.
Mol.Biol.Cell, 33, 2022
8IQF
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BU of 8iqf by Molmil
Cryo-EM structure of the dimeric human CAF1-H3-H4 complex
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
著者Liu, C.P, Yu, Z.Y, Xu, R.M.
登録日2023-03-16
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7AT8
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BU of 7at8 by Molmil
Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2.
分子名称: Histone H2A, Histone H2B 1.1, Histone H3.2, ...
著者Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J.
登録日2020-10-29
公開日2020-12-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3.
Elife, 9, 2020
7KLO
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BU of 7klo by Molmil
Solution structure of the PHD1 domain of histone demethylase KDM5A
分子名称: Lysine-specific demethylase 5A, ZINC ION
著者Longbotham, E.J, Kelly, M.J.S, Fujimori, D.G.
登録日2020-10-30
公開日2021-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.
Acs Chem.Biol., 2021
8IQG
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BU of 8iqg by Molmil
Cryo-EM structure of the monomeric human CAF1-H3-H4 complex
分子名称: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
著者Liu, C.P, Yu, Z.Y, Xu, R.M.
登録日2023-03-16
公開日2023-08-16
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
5J9S
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BU of 5j9s by Molmil
ENL YEATS in complex with histone H3 acetylation at K27
分子名称: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION
著者Li, Y, Li, H.
登録日2016-04-11
公開日2017-03-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
Nature, 543, 2017
1PEG
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BU of 1peg by Molmil
Structural basis for the product specificity of histone lysine methyltransferases
分子名称: Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X.
登録日2003-05-21
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
8JLA
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BU of 8jla by Molmil
Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4
分子名称: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8F8Z
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BU of 8f8z by Molmil
PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8SWI
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BU of 8swi by Molmil
Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide
分子名称: Eukaryotic huntingtin interacting protein B, Histone H3 peptided, S-ADENOSYL-L-HOMOCYSTEINE
著者Xu, C, Chung, I.Y.W, Cygler, M.
登録日2023-05-18
公開日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.
Mbio, 14, 2023
7QCE
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BU of 7qce by Molmil
Crystal structure of an atypical PHD finger of VIN3
分子名称: DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION
著者Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M.
登録日2021-11-23
公開日2022-11-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023

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