5J9S

ENL YEATS in complex with histone H3 acetylation at K27

Summary for 5J9S

• Entry DOI: 10.2210/pdb5j9s/pdb
• Descriptor: Protein ENL, H3K27ac peptide from Histone H3.1, SULFATE ION, ... (4 entities in total)
• Functional Keywords: complex, enl yeats, histone acetyllysine, h3k27, transcription
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q03111 P68431
• Total number of polymer chains: 2
• Total formula weight: 21315.43

Authors

Li, Y.,Li, H. (deposition date: 2016-04-11, release date: 2017-03-08, Last modification date: 2023-11-15)

• Primary citation: Wan, L.,Wen, H.,Li, Y.,Lyu, J.,Xi, Y.,Hoshii, T.,Joseph, J.K.,Wang, X.,Loh, Y.E.,Erb, M.A.,Souza, A.L.,Bradner, J.E.,Shen, L.,Li, W.,Li, H.,Allis, C.D.,Armstrong, S.A.,Shi, X.; ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia; Nature, 543:265-269, 2017; PubMed: 28241141; DOI: 10.1038/nature21687

Experimental method

X-RAY DIFFRACTION (2.702 Å)