8JLA

Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4

Summary for 8JLA

Entry DOI	10.2210/pdb8jla/pdb
EMDB information	36390
Descriptor	Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total)
Functional Keywords	nuclear protein, chromatin, gene regulation-dna complex, gene regulation/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	216294.23
Authors	Oishi, T.,Hatazawa, S.,Kujirai, T.,Kato, J.,Kobayashi, Y.,Ogasawara, M.,Akatsu, M.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2023-06-02, release date: 2023-10-04, Last modification date: 2023-11-08)
Primary citation	Oishi, T.,Hatazawa, S.,Kujirai, T.,Kato, J.,Kobayashi, Y.,Ogasawara, M.,Akatsu, M.,Ehara, H.,Sekine, S.I.,Hayashi, G.,Takizawa, Y.,Kurumizaka, H. Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51:10364-10374, 2023 Cited by PubMed: 37718728 DOI: 10.1093/nar/gkad754 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.44 Å)

Structure validation