7OKP

Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated

Summary for 7OKP

Entry DOI	10.2210/pdb7okp/pdb
Descriptor	Histone-arginine methyltransferase CARM1, Histone H3.3, MALONATE ION, ... (5 entities in total)
Functional Keywords	protein arginine n-methyltransferase, prmt, carm1, transition state mimics, transcription
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	8
Total formula weight	174119.29
Authors	Marechal, N.,Cura, V.,Troffer-Charlier, N.,Bonnefond, L.,Cavarelli, J. (deposition date: 2021-05-18, release date: 2021-10-27, Last modification date: 2024-01-31)
Primary citation	Zhang, Y.,Marechal, N.,van Haren, M.J.,Troffer-Charlier, N.,Cura, V.,Cavarelli, J.,Martin, N.I. Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors. Chembiochem, 22:3469-3476, 2021 Cited by PubMed: 34569136 DOI: 10.1002/cbic.202100506 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation