7OKP
Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histone-arginine methyltransferase CARM1 | polymer | 371 | 41985.6 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) | Mus musculus (Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | E, F, G, H (E, F, G, H) | Histone H3.3 | polymer | 11 | 1139.3 | 4 | UniProt (P84243) | Homo sapiens | |
| 3 | I, J, K, L, M (B, C, D) | MALONATE ION | non-polymer | 102.0 | 5 | Chemie (MLI) | |||
| 4 | N, O, P, Q (E, F, G, H) | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol | non-polymer | 277.3 | 4 | Chemie (QVR) | |||
| 5 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 497 (UniProt: Q9WVG6)
E, F, G, H: 13 - 22 (UniProt: P84243)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 12 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 172499.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1619.3 | |
| All* | Total formula weight | 174119.3 |
