PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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3H3Z	Crystal structure of a putative cyclic nucleotide binding protein (spoa0323) from ruegeria pomeroyi dss-3 at 2.35 A resolution 分子名称: CHLORIDE ION, Cyclic nucleotide-binding protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-04-17 公開日 2009-05-05 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of PUTATIVE CAMP-BINDING REGULATORY PROTEIN (YP_165150.1) from SILICIBACTER POMEROYI DSS-3 at 2.35 A resolution To be published
7KRC	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with (E)-4-(3-chloro-5-(2-cyanovinyl)phenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenyl sulfurofluoridate (JLJ709) 分子名称: 4-{3-chloro-5-[(E)-2-cyanoethenyl]phenoxy}-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Bertoletti, N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. 登録日 2020-11-19 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. Acs Med.Chem.Lett., 12, 2021
5J30	Thermus thermophilus 70S termination complex containing E. coli RF1 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hoffer, E.D, Dunham, C.M. 登録日 2016-03-30 公開日 2016-10-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
8RXA	ACDC domain of AP2-O5 from Plasmodium falciparum 分子名称: AP2 domain transcription factor AP2-O5, putative 著者 Nessler, S, Le Berre, M, Gallay Li de la Sierra, I. 登録日 2024-02-06 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Structural characterization of the ACDC domain from ApiAP2 proteins of the malaria parasite. Biorxiv, 2024
5J4C	Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. 登録日 2016-03-31 公開日 2016-04-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
8RWU	ACDC domain of the AP2-I transcription factor from Plasmodium vivax 分子名称: AP2 domain transcription factor AP2-I, putative 著者 Nessler, S, Le Berre, M, Gallay Li de la Sierra, I. 登録日 2024-02-05 公開日 2024-03-06 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (3.152 Å) 主引用文献 Structural characterization of the ACDC domain from ApiAP2 proteins of the malaria parasite. Biorxiv, 2024
8FC3	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.60A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
7JY5	Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97) 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Pan, M, Yu, Y, Liu, L, Zhao, M. 登録日 2020-08-28 公開日 2021-01-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun, 12, 2021
3HAZ	Crystal structure of bifunctional proline utilization A (PutA) protein 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Tanner, J.J. 登録日 2009-05-03 公開日 2010-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum Proc.Natl.Acad.Sci.USA, 107, 2010
8RXO	ACDC domain of Plasmodium falciparum AP2-I transcription factor 分子名称: AP2 domain transcription factor AP2-I 著者 Nessler, S, Le Berre, M, Li De La Sierra, I. 登録日 2024-02-07 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.998 Å) 主引用文献 Structural characterization of the ACDC domain from ApiAP2 proteins of the malaria parasite. Biorxiv, 2024
5J4D	E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon 分子名称: 16S ribosomal RNA, 25S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2016-03-31 公開日 2016-05-18 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis for Translation Termination on a Pseudouridylated Stop Codon. J.Mol.Biol., 428, 2016
2FSO	mitogen activated protein kinase p38alpha (D176A) activating mutant 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
2FSL	mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
3HZF	Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group 分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid 著者 Aparicio, R, Bleicher, L, Polikarpov, I. 登録日 2009-06-23 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8, 2008
8FC6	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC2	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.50A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8G2C	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with tylosin, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.65A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. 登録日 2023-02-03 公開日 2023-12-27 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 20, 2024
8G2B	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAphe, and aminoacylated P-site fMet-tRNAmet at 2.55A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. 登録日 2023-02-03 公開日 2023-12-27 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 20, 2024
8G2A	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-tRNAphe, peptidyl P-site fMTHSMRC-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. 登録日 2023-02-03 公開日 2023-12-27 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 20, 2024
8FC5	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.65A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8FC4	Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.45A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
7KJX	Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine 分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
7KJW	Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz 分子名称: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
7KJV	Structure of HIV-1 reverse transcriptase initiation complex core 分子名称: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
8SHU	Structure of mouse cGAS 分子名称: Cyclic GMP-AMP synthase, ZINC ION 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024

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