2QAR
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1P2F
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2QH2
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2IWJ
| SOLUTION STRUCTURE OF THE ZN COMPLEX OF HIV-2 NCP(23-49) PEPTIDE, ENCOMPASSING PROTEIN CCHC-LINKER, DISTAL CCHC ZN-BINDING MOTIF AND C- TERMINAL TAIL. | 分子名称: | GAG-POL POLYPROTEIN, ZINC ION | 著者 | Amodeo, P, Castiglione Morelli, M.A, Ostuni, A, Cristinziano, P, Bavoso, A. | 登録日 | 2006-06-30 | 公開日 | 2007-10-09 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Features of the C-Terminal Zinc Finger Domain of the HIV-2 Nc Protein (Residues 23-49). To be Published
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2QB6
| Saccharomyces cerevisiae cytosolic exopolyphosphatase, sulfate complex | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Exopolyphosphatase, ... | 著者 | White, S.A, Ugochukwu, E. | 登録日 | 2007-06-16 | 公開日 | 2007-12-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of the cytosolic exopolyphosphatase from Saccharomyces cerevisiae reveals the basis for substrate specificity. J.Mol.Biol., 371, 2007
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3KVV
| Trapping of an oxocarbenium ion intermediate in UP crystals | 分子名称: | 1,4-anhydro-D-erythro-pent-1-enitol, 5-FLUOROURACIL, SULFATE ION, ... | 著者 | Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. | 登録日 | 2009-11-30 | 公開日 | 2010-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
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2QZS
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3KZX
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2QHO
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3L0S
| Crystal structures of Zinc, Cobalt and Iron containing Adenylate kinase from Gram-negative bacteria Desulfovibrio gigas | 分子名称: | Adenylate kinase, COBALT (II) ION, D(-)-TARTARIC ACID | 著者 | Mukhopadhyay, A, Trincao, J, Romao, M.J. | 登録日 | 2009-12-10 | 公開日 | 2010-12-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the zinc-, cobalt-, and iron-containing adenylate kinase from Desulfovibrio gigas: a novel metal-containing adenylate kinase from Gram-negative bacteria J.Biol.Inorg.Chem., 16, 2011
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2QEQ
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2QFC
| Crystal Structure of Bacillus thuringiensis PlcR complexed with PapR | 分子名称: | C-terminus pentapeptide from PapR protein, DI(HYDROXYETHYL)ETHER, PlcR protein | 著者 | Declerck, N, Chaix, D, Rugani, N, Hoh, F, Arold, S.T. | 登録日 | 2007-06-27 | 公開日 | 2007-11-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R18
| Structural insights into the multifunctional protein VP3 of Birnaviruses | 分子名称: | Capsid assembly protein VP3 | 著者 | Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. | 登録日 | 2007-08-22 | 公開日 | 2008-02-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the multifunctional protein VP3 of birnaviruses. Structure, 16, 2008
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2DA5
| Solution structure of the second homeobox domain of Zinc fingers and homeoboxes protein 3 (Triple homeobox 1 protein) | 分子名称: | Zinc fingers and homeoboxes protein 3 | 著者 | Ohnishi, S, Kigawa, T, Saito, K, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-12-13 | 公開日 | 2006-06-13 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the second homeobox domain of Zinc fingers and homeoboxes protein 3 (Triple homeobox 1 protein) To be Published
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2R4U
| Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSd) | 分子名称: | (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Sheng, F, Geiger, J. | 登録日 | 2007-09-01 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.367 Å) | 主引用文献 | The crystal structures of the open and catalytically competent closed conformation of Escherichia coli glycogen synthase. J.Biol.Chem., 284, 2009
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4IW2
| HSA-glucose complex | 分子名称: | D-glucose, PHOSPHATE ION, Serum albumin, ... | 著者 | Wang, Y, Yu, H, Shi, X, Luo, Z, Huang, M. | 登録日 | 2013-01-23 | 公開日 | 2013-04-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structural mechanism of ring-opening reaction of glucose by human serum albumin J.Biol.Chem., 288, 2013
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2C3L
| Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification | 分子名称: | 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION | 著者 | Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A. | 登録日 | 2005-10-10 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification. Bioorg.Med.Chem., 14, 2006
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8B6C
| Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147 | 分子名称: | 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ... | 著者 | Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K. | 登録日 | 2022-09-26 | 公開日 | 2023-02-22 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9, 2023
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8B5L
| Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K. | 登録日 | 2022-09-23 | 公開日 | 2023-03-01 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9, 2023
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2REW
| Crystal Structure of PPARalpha ligand binding domain with BMS-631707 | 分子名称: | (2S,3S)-1-(4-METHOXYPHENYL)-3-(3-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)BENZYL)-4-OXOAZETIDINE-2-CARBOXYLIC ACID, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE, Peroxisome proliferator-activated receptor alpha | 著者 | Muckelbauer, J. | 登録日 | 2007-09-27 | 公開日 | 2007-11-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery of Azetidinone Acids as Conformationally-Constrained Dual (alpha/gamma) PPAR Activators To be Published
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8W8D
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8EZ0
| Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Symmetric conformation | 分子名称: | Insulin, Insulin receptor | 著者 | Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. | 登録日 | 2022-10-29 | 公開日 | 2022-11-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor. Elife, 11, 2022
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8EYX
| Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 1 | 分子名称: | Insulin, Insulin receptor | 著者 | Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. | 登録日 | 2022-10-29 | 公開日 | 2022-11-09 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor. Elife, 11, 2022
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8EYY
| Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S, denoted as IR-3CS) Asymmetric conformation 2 | 分子名称: | Insulin, Insulin receptor | 著者 | Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. | 登録日 | 2022-10-29 | 公開日 | 2022-11-09 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor. Elife, 11, 2022
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8F1G
| Crystal structure of human WDR5 in complex with compound WM662 | 分子名称: | (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid, GLYCEROL, SULFATE ION, ... | 著者 | Liu, H. | 登録日 | 2022-11-05 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. Acs Chem.Biol., 18, 2023
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