PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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5YV0	DNA polymerase IV - DNA ternary complex 12 分子名称: DIPHOSPHATE, DNA polymerase IV, DTN1, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-11-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction. Nucleic Acids Res., 46, 2018
3TO7	Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated 分子名称: CACODYLIC ACID, COENZYME A, GLYCEROL, ... 著者 Yuan, H, Ding, E.C, Marmorstein, R. 登録日 2011-09-04 公開日 2011-11-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
7KND	C1B domain of Protein kinase C in apo form 分子名称: Protein kinase C delta type, ZINC ION 著者 Katti, S.S, Krieger, I. 登録日 2020-11-04 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7KO6	C1B domain of Protein kinase C in complex with ingenol-3-angelate and phosphocholine 分子名称: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... 著者 Katti, S.S, Krieger, I.V. 登録日 2020-11-06 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7D90	human potassium-chloride co-transporter KCC3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 3 著者 Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. 登録日 2020-10-12 公開日 2020-12-30 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
4JQ0	Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin 分子名称: CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ... 著者 Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S. 登録日 2013-03-19 公開日 2014-05-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.84 Å) 主引用文献 Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nat Commun, 5, 2014
7KNJ	C1B domain of Protein kinase C in complex with Phorbol ester and Phosphatidylcholine 分子名称: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Phorbol 12,13-dibutyrate, Protein kinase C delta type, ... 著者 Katti, S.S, Krieger, I. 登録日 2020-11-04 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
5Z7D	p204HINab-dsDNA complex structure 分子名称: DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204 著者 Jin, T, Jiang, J, Xiao, T.S. 登録日 2018-01-28 公開日 2019-01-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res., 2021
1X7G	Actinorhodin Polyketide Ketoreductase, act KR, with NADP bound 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase 著者 Korman, T.P, Hill, J.A, Vu, T.N. 登録日 2004-08-13 公開日 2004-12-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity Biochemistry, 43, 2004
5AYZ	CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE 分子名称: NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide pyrophosphorylase [carboxylating] 著者 Youn, H.S, Kim, T.G, Kim, M.K, Kang, G.B, Kang, J.Y, Seo, Y.J, Lee, J.G, An, J.Y, Park, K.R, Lee, Y, Im, Y.J, Lee, J.H, Fukuoka, S.I, Eom, S.H. 登録日 2015-09-14 公開日 2016-02-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis Sci Rep, 6, 2016
4IT3	Crystal Structure of Iml3 from S. cerevisiae 分子名称: Central kinetochore subunit IML3 著者 Hinshaw, S.M, Harrison, S.C. 登録日 2013-01-17 公開日 2013-10-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 An iml3-chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. Cell Rep, 5, 2013
4TUS	Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE. 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2014-06-24 公開日 2014-10-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta. J.Biol.Chem., 289, 2014
3U9J	Crystal structure of oxidized human FBXL5 hemerythrin like domain 分子名称: F-box/LRR-repeat protein 5, FE (III) ION 著者 Li, P. 登録日 2011-10-19 公開日 2012-02-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5. Chembiochem, 13, 2012
5ZDE	Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Deinococcus radiodurans in complex with ADP-ribose (P3221) 分子名称: Poly ADP-ribose glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Cho, C.C, Hsu, C.H. 登録日 2018-02-23 公開日 2019-02-27 最終更新日 2020-03-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans. Nat Commun, 10, 2019
3U2C	Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution 分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Aldose reductase, CITRIC ACID, ... 著者 Steuber, H. 登録日 2011-10-03 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 An old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 A supports a novel mechanism for its anticancer and antiproliferative effects. Chemmedchem, 6, 2011
1XCZ	Structure of DNA containing the beta-anomer of a carbocyclic abasic site 分子名称: 5'-D(*CP*GP*TP*AP*CP*(DXD)P*CP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*GP*AP*GP*TP*AP*CP*G)-3' 著者 de los Santos, C, El-khateeb, M, Rege, P, Tian, K, Johnson, F. 登録日 2004-09-03 公開日 2004-10-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Impact of the C1 configuration of abasic sites on DNA duplex structure Biochemistry, 43, 2004
5ZBL	Crystal structure of type-I LOG from Corynebacterium glutamicum in complex with AMP 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Cytokinin riboside 5'-monophosphate phosphoribohydrolase, ... 著者 Seo, H, Kim, K.-J. 登録日 2018-02-12 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insight into molecular mechanism of cytokinin activating protein from Pseudomonas aeruginosa PAO1. Environ. Microbiol., 20, 2018
5Z0B	Crystal structure of plasma-derived human serum albumin 分子名称: DI(HYDROXYETHYL)ETHER, LINOLEIC ACID, OCTANOIC ACID (CAPRYLIC ACID), ... 著者 Park, J, Kim, M.-S, Shin, D.H. 登録日 2017-12-19 公開日 2018-12-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 The crystal structure of plasma-derived human serum albumin To Be Published
4QIY	Crystal structure of human carbonic anhydrase isozyme II with inhibitor 分子名称: 2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Manakova, E, Smirnov, A, Grazulis, S. 登録日 2014-06-03 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10, 2015
5D48	Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid 分子名称: 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy)phenyl]-1H-indol-1-yl}propanoic acid, Fatty acid-binding protein, adipocyte, ... 著者 Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. 登録日 2015-08-07 公開日 2016-06-22 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7, 2016
4QHP	Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe(4-CH2NH2) 分子名称: (2R)-2-[4-(aminomethyl)benzyl]-3-[(R)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]propanoic acid, (2S)-2-[4-(aminomethyl)benzyl]-3-[(R)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]propanoic acid, Aminopeptidase N, ... 著者 Nocek, B, Joachimiak, A. 登録日 2014-05-28 公開日 2014-09-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
4QK1	Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - K170P 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Rasi, V, McKenna, R. 登録日 2014-06-05 公開日 2015-03-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. Febs J., 282, 2015
4QIW	Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis 分子名称: DNA-directed RNA polymerase, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... 著者 Jun, S.-H, Murakami, K.S. 登録日 2014-06-02 公開日 2014-10-08 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration. Nat Commun, 5, 2014
3Q6L	Crystal Structure of Human Adipocyte Fatty Acid Binding Protein (FABP4) at 1.4 Ang. Resolution 分子名称: Fatty acid-binding protein, adipocyte 著者 Prasad, G.S, Carney, D, Small, V, Sankaran, B, Zwart, P.H. 登録日 2011-01-02 公開日 2011-01-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of Human Adipocyte Fatty Acid Binding Protein (FABP4) at 1.4 Ang. Resolution To be Published
1AC9	SOLUTION STRUCTURE OF A DNA DECAMER CONTAINING THE ANTIVIRAL DRUG GANCICLOVIR: COMBINED USE OF NMR, RESTRAINED MOLECULAR DYNAMICS, AND FULL RELAXATION REFINEMENT, 6 STRUCTURES 分子名称: DNA 著者 Foti, M, Marshalko, S, Schurter, E, Kumar, S, Beardsley, G.P, Schweitzer, B.I. 登録日 1997-02-17 公開日 1997-07-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a DNA decamer containing the antiviral drug ganciclovir: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement. Biochemistry, 36, 1997

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