7KNJ
C1B domain of Protein kinase C in complex with Phorbol ester and Phosphatidylcholine
Summary for 7KNJ
Entry DOI | 10.2210/pdb7knj/pdb |
Descriptor | Protein kinase C delta type, (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, ZINC ION, ... (5 entities in total) |
Functional Keywords | c1, lipid-binding, phorbol ester binding, zn2+ finger, lipid binding protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 1 |
Total formula weight | 7697.78 |
Authors | Katti, S.S.,Krieger, I. (deposition date: 2020-11-04, release date: 2022-05-04, Last modification date: 2023-10-18) |
Primary citation | Katti, S.S.,Krieger, I.V.,Ann, J.,Lee, J.,Sacchettini, J.C.,Igumenova, T.I. Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13:2695-2695, 2022 Cited by PubMed: 35577811DOI: 10.1038/s41467-022-30389-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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