5AYZ
CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE
Replaces: 4R3YSummary for 5AYZ
Entry DOI | 10.2210/pdb5ayz/pdb |
Related | 4R3X |
Descriptor | Nicotinate-nucleotide pyrophosphorylase [carboxylating], NICOTINATE MONONUCLEOTIDE (3 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 12 |
Total formula weight | 387022.19 |
Authors | Youn, H.S.,Kim, T.G.,Kim, M.K.,Kang, G.B.,Kang, J.Y.,Seo, Y.J.,Lee, J.G.,An, J.Y.,Park, K.R.,Lee, Y.,Im, Y.J.,Lee, J.H.,Fukuoka, S.I.,Eom, S.H. (deposition date: 2015-09-14, release date: 2016-02-03, Last modification date: 2023-11-08) |
Primary citation | Youn, H.S.,Kim, T.G.,Kim, M.K.,Kang, G.B.,Kang, J.Y.,Lee, J.G.,An, J.Y.,Park, K.R.,Lee, Y.,Im, Y.J.,Lee, J.H.,Eom, S.H. Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis Sci Rep, 6:19681-19681, 2016 Cited by PubMed: 26805589DOI: 10.1038/srep19681 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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