5AYZ

CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE

Replaces:  4R3Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	polymer	305	31916.6	12	UniProt (V9HWJ5) Pfam (PF02749) Pfam (PF01729) UniProt (by SIFTS) (Q15274) In PDB	Homo sapiens (Human)	Quinolinate phosphoribosyltransferase [decarboxylating]
2	A, B, C, D, E...	NICOTINATE MONONUCLEOTIDE	non-polymer		335.2	12	Chemie (NCN)
3		water	water		18.0	254	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 297 (UniProt: V9HWJ5)

PDB	External Database	Details
Leu 298	-	expression tag
Glu 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	382999.7
Non-Polymers*	Number of molecules	12
	Total formula weight	4022.4
All*	Total formula weight	387022.2

*Water molecules are not included.