Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - K170P

Summary for 4QK1

Related4QK2 4QK3
DescriptorCarbonic anhydrase 2, ZINC ION (3 entities in total)
Functional Keywordslyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P00918
Total number of polymer chains1
Total molecular weight29322.41
Boone, C.D.,Rasi, V.,McKenna, R. (deposition date: 2014-06-05, release date: 2015-03-04, Last modification date: 2017-11-22)
Primary citation
Boone, C.D.,Rasi, V.,Tu, C.,McKenna, R.
Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II.
Febs J., 282:1445-1457, 2015
PubMed: 25683338 (PDB entries with the same primary citation)
DOI: 10.1111/febs.13232
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2213 0.4% 3.6% 4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21