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4QK1

Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - K170P

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029257.01UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
waterwater18.0193Chemie (HOH)
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDBExternal DatabaseDetails
Pro 170Lys 169engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29257.0
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight29322.4
*Water molecules are not included.

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PDB entries from 2026-04-01

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