1X7G

Actinorhodin Polyketide Ketoreductase, act KR, with NADP bound

Summary for 1X7G

Entry DOI	10.2210/pdb1x7g/pdb
Related	1X7H
Descriptor	Putative ketoacyl reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	polyketide, ketoreductase, short chain dehydrogenase/reductase, combinatorial biosynthesis, actinorhodin, antibiotic, oxidoreductase
Biological source	Streptomyces coelicolor
Total number of polymer chains	2
Total formula weight	56072.84
Authors	Korman, T.P.,Hill, J.A.,Vu, T.N. (deposition date: 2004-08-13, release date: 2004-12-14, Last modification date: 2024-02-14)
Primary citation	Korman, T.P.,Hill, J.A.,Vu, T.N.,Tsai, S.C. Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity Biochemistry, 43:14529-14538, 2004 Cited by PubMed: 15544323 DOI: 10.1021/bi048133a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation