3H9S
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5MEP
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![BU of 5mep by Molmil](/molmil-images/mine/5mep) | Human Leukocyte Antigen A02 presenting ILGKFLHWL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K. | 登録日 | 2016-11-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
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3UTS
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![BU of 3uts by Molmil](/molmil-images/mine/3uts) | 1E6-A*0201-ALWGPDPAAA Complex, Monoclinic | 分子名称: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (2.712 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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4FTV
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![BU of 4ftv by Molmil](/molmil-images/mine/4ftv) | |
4MNQ
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![BU of 4mnq by Molmil](/molmil-images/mine/4mnq) | TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Jakobsen, B.K. | 登録日 | 2013-09-11 | 公開日 | 2013-11-13 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (2.742 Å) | 主引用文献 | T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions. J.Biol.Chem., 289, 2014
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6D7G
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![BU of 6d7g by Molmil](/molmil-images/mine/6d7g) | Structure of 5F3 TCR in complex with HLA-A2/MART-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ... | 著者 | Roy, S, Adams, E.J. | 登録日 | 2018-04-24 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells. Sci Immunol, 3, 2018
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5NMG
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![BU of 5nmg by Molmil](/molmil-images/mine/5nmg) | 868 TCR in complex with HLA A02 presenting SLYFNTIAVL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2017-04-05 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
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4GKN
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![BU of 4gkn by Molmil](/molmil-images/mine/4gkn) | A2-MHC Complex carrying FATGIGIITV | 分子名称: | Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ... | 著者 | Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A. | 登録日 | 2012-08-13 | 公開日 | 2012-09-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | 主引用文献 | T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting. J.Biol.Chem., 287, 2012
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5WWU
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![BU of 5wwu by Molmil](/molmil-images/mine/5wwu) | Crystal Structure of HLA-A*2402 in complex with 2009 pandemic influenza A(H1N1) virus and avian influenza A(H5N1) virus-derived peptide H1-25 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2017-01-05 | 公開日 | 2018-01-17 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. Mbio, 9, 2018
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3QZW
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![BU of 3qzw by Molmil](/molmil-images/mine/3qzw) | Plasticity of human CD8 binding to peptide-HLA-A*2402 | 分子名称: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2011-03-07 | 公開日 | 2011-06-29 | 最終更新日 | 2013-07-03 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402 Mol.Immunol., 48, 2011
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4I48
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![BU of 4i48 by Molmil](/molmil-images/mine/4i48) | Structure of HLA-A68 complexed with an HIV Env derived peptide | 分子名称: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2012-11-27 | 公開日 | 2013-10-02 | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
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3I6K
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![BU of 3i6k by Molmil](/molmil-images/mine/3i6k) | Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Liu, J, Sun, Y, Qi, J, Chu, F, Wu, H, Gao, F, Li, T, Yan, J, Gao, G.F. | 登録日 | 2009-07-07 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes J Infect Dis, 202, 2010
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3D3V
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![BU of 3d3v by Molmil](/molmil-images/mine/3d3v) | The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide | 分子名称: | A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ... | 著者 | Borbulevych, O.Y, Clemens, J.R, Baker, B.M. | 登録日 | 2008-05-12 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner. Biochem.J., 423, 2009
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1I7T
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![BU of 1i7t by Molmil](/molmil-images/mine/1i7t) | CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-5V | 分子名称: | 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J. | 登録日 | 2001-03-10 | 公開日 | 2001-10-24 | 最終更新日 | 2021-07-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface J.Biol.Chem., 276, 2001
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2BCK
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![BU of 2bck by Molmil](/molmil-images/mine/2bck) | Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F. | 登録日 | 2005-10-19 | 公開日 | 2006-01-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of HLA-A*2402 complexed with a telomerase peptide. Eur.J.Immunol., 36, 2006
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1I1F
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![BU of 1i1f by Molmil](/molmil-images/mine/1i1f) | Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt variant peptide i1y | 分子名称: | PROTEIN (BETA 2-MICROGLOBULIN), PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-A0201 ALPHA CHAIN), ... | 著者 | Kirksey, T.J, Pogue-Caley, R.R, Frelinger, J.A, Collins, E.J. | 登録日 | 1999-04-16 | 公開日 | 2000-01-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes. J.Biol.Chem., 274, 1999
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1QSE
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![BU of 1qse by Molmil](/molmil-images/mine/1qse) | STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R | 分子名称: | PROTEIN (MHC class I HLA-A), PROTEIN (beta-2 microglobulin), PROTEIN (human T-Cell receptor), ... | 著者 | Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C. | 登録日 | 1999-06-21 | 公開日 | 1999-12-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity, 11, 1999
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1QSF
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![BU of 1qsf by Molmil](/molmil-images/mine/1qsf) | STRUCTURE OF A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE Y8A | 分子名称: | BETA-2 MICROGLOBULIN, HUMAN T-CELL RECEPTOR, MHC CLASS I HLA-A, ... | 著者 | Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C. | 登録日 | 1999-06-21 | 公開日 | 1999-12-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity, 11, 1999
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1QRN
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![BU of 1qrn by Molmil](/molmil-images/mine/1qrn) | CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A | 分子名称: | BETA-2 MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ... | 著者 | Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C. | 登録日 | 1999-06-14 | 公開日 | 1999-10-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity, 11, 1999
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3GSN
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![BU of 3gsn by Molmil](/molmil-images/mine/3gsn) | Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ... | 著者 | Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
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3QDM
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6EQB
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![BU of 6eqb by Molmil](/molmil-images/mine/6eqb) | HLA class I histocompatibility antigen | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | 著者 | Rizkallah, P.J, Cole, D.K. | 登録日 | 2017-10-12 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | TCR-induced alteration of primary MHC peptide anchor residue. Eur.J.Immunol., 49, 2019
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5MEN
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![BU of 5men by Molmil](/molmil-images/mine/5men) | Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. | 登録日 | 2016-11-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
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3D39
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![BU of 3d39 by Molmil](/molmil-images/mine/3d39) | The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide | 分子名称: | A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ... | 著者 | Borbulevych, O.Y, Clemens, J.R, Baker, B.M. | 登録日 | 2008-05-09 | 公開日 | 2009-06-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner Biochem.J., 423, 2009
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5WJN
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![BU of 5wjn by Molmil](/molmil-images/mine/5wjn) | Crystal Structure of HLA-A*11:01-GTS3 | 分子名称: | Beta-2-microglobulin, GTS3 peptide, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Rossjohn, J. | 登録日 | 2017-07-23 | 公開日 | 2017-09-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response. Nat. Immunol., 18, 2017
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