4I48

Structure of HLA-A68 complexed with an HIV Env derived peptide

Summary for 4I48

• Entry DOI: 10.2210/pdb4i48/pdb
• Related: 4HWZ 4HX1
• Descriptor: HLA class I histocompatibility antigen, A-68 alpha chain, Beta-2-microglobulin, 9-mer peptide from Envelope glycoprotein gp160, ... (4 entities in total)
• Functional Keywords: monomer, peptide presentation, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01891; Secreted: P61769; Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626
• Total number of polymer chains: 3
• Total formula weight: 44451.29

Authors

Niu, L.,Cheng, H.,Zhang, S.,Tan, S.,Zhang, Y.,Qi, J.,Liu, J.,Gao, G.F. (deposition date: 2012-11-27, release date: 2013-10-02)

• Primary citation: Niu, L.,Cheng, H.,Zhang, S.,Tan, S.,Zhang, Y.,Qi, J.,Liu, J.,Gao, G.F.; Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes; Mol.Immunol., 55:381-392, 2013; PubMed: 23566939; DOI: 10.1016/j.molimm.2013.03.015

Experimental method

X-RAY DIFFRACTION (2.799 Å)