8HQY
 
 | | Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom | | 分子名称: | DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... | | 著者 | Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
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7U51
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7BQZ
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6Y5E
 | | Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex) | | 分子名称: | Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-C, ... | | 著者 | Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H. | | 登録日 | 2020-02-25 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structural mechanism of cGAS inhibition by the nucleosome.
Nature, 587, 2020
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7UV9
 | | KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate | | 分子名称: | DNA (185-MER), FE (III) ION, Histone H2A type 1, ... | | 著者 | Spangler, C.J, Skrajna, A, Foley, C.A, Budziszewski, G.R, Azzam, D.N, James, L.I, Frye, S.V, McGinty, R.K. | | 登録日 | 2022-04-29 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
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7YRD
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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6T79
 | | Structure of a human nucleosome at 3.2 A resolution | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | | 登録日 | 2019-10-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
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8X7K
 | | Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by activity-based chemical trapping strategy (adjacent H2AK13/15 dual-monoubiquitination) | | 分子名称: | DNA (143-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | | 登録日 | 2023-11-24 | | 公開日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Biorxiv, 2024
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8X7I
 | | Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by intein-based E2-Ub-NCP conjugation strategy | | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | | 登録日 | 2023-11-24 | | 公開日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Biorxiv, 2024
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7JO9
 | | 1:1 cGAS-nucleosome complex | | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | | 著者 | Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. | | 登録日 | 2020-08-06 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of nucleosome-dependent cGAS inhibition.
Science, 370, 2020
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7JOA
 | | 2:1 cGAS-nucleosome complex | | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | | 著者 | Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. | | 登録日 | 2020-08-06 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of nucleosome-dependent cGAS inhibition.
Science, 370, 2020
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5B40
 | | The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Machida, S, Sekine, S, Nishiyama, Y, Horikoshi, N, Kurumizaka, H. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | | 主引用文献 | Monoubiquitination of histones H2B and H4 changes the nucleosome stability without affecting the nucleosome structure
To Be Published
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8X7J
 | | Cryo-EM structures of RNF168/UbcH5c-Ub/nucleosomes complex determined by activity-based chemical trapping strategy | | 分子名称: | DNA (144-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | | 登録日 | 2023-11-24 | | 公開日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Biorxiv, 2024
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7U50
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7U52
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8ATF
 | | Nucleosome-bound Ino80 ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-08-23 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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7XD0
 | | cryo-EM structure of H2BK34ub nucleosome | | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-26 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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8OL1
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7BU9
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6T7A
 | | Structure of human Sox11 transcription factor in complex with a nucleosome | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | | 登録日 | 2019-10-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
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7PF5
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8GRQ
 | | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | | 分子名称: | BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ... | | 著者 | Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. | | 登録日 | 2022-09-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
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7JZV
 | | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | | 登録日 | 2020-09-02 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
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7PF3
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7PF4
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