7UV9

KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate

Summary for 7UV9

Entry DOI	10.2210/pdb7uv9/pdb
EMDB information	26809 26810
Descriptor	Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total)
Functional Keywords	chromatin nucleosome lysine demethylase jmjc protein, gene regulation-dna complex, gene regulation/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	11
Total formula weight	302955.70
Authors	Spangler, C.J.,Skrajna, A.,Foley, C.A.,Budziszewski, G.R.,Azzam, D.N.,James, L.I.,Frye, S.V.,McGinty, R.K. (deposition date: 2022-04-29, release date: 2023-02-22, Last modification date: 2023-05-17)
Primary citation	Spangler, C.J.,Skrajna, A.,Foley, C.A.,Nguyen, A.,Budziszewski, G.R.,Azzam, D.N.,Arteaga, E.C.,Simmons, H.C.,Smith, C.B.,Wesley, N.A.,Wilkerson, E.M.,McPherson, J.E.,Kireev, D.,James, L.I.,Frye, S.V.,Goldfarb, D.,McGinty, R.K. Structural basis of paralog-specific KDM2A/B nucleosome recognition. Nat.Chem.Biol., 19:624-632, 2023 Cited by PubMed: 36797403 DOI: 10.1038/s41589-023-01256-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation