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8GRQ

Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome

Summary for 8GRQ
Entry DOI10.2210/pdb8grq/pdb
EMDB information34212
DescriptorHistone H3, ZINC ION, Histone H4, ... (10 entities in total)
Functional Keywordsnucleosome, brca1/bard1, brca1, bard1, h2ak127, h2ak127-ubch5c-ub, nuclear protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains13
Total formula weight235960.68
Authors
Ai, H.S.,Zebin, T.,Zhiheng, D.,Jiakun, T.,Liying, Z.,Jia-Bin, L.,Man, P.,Liu, L. (deposition date: 2022-09-02, release date: 2023-04-12, Last modification date: 2024-07-03)
Primary citationAi, H.S.,Tong, Z.,Deng, Z.,Tian, J.,Zhang, L.,Sun, M.,Du, Y.,Xu, Z.,Shi, Q.,Liang, L.,Zheng, Q.,Li, J.B.,Pan, M.,Liu, L.
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
Cited by
DOI: 10.1016/j.chempr.2023.01.012
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.87 Å)
Structure validation

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