8GRQ
Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome
Summary for 8GRQ
Entry DOI | 10.2210/pdb8grq/pdb |
EMDB information | 34212 |
Descriptor | Histone H3, ZINC ION, Histone H4, ... (10 entities in total) |
Functional Keywords | nucleosome, brca1/bard1, brca1, bard1, h2ak127, h2ak127-ubch5c-ub, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 13 |
Total formula weight | 235960.68 |
Authors | Ai, H.S.,Zebin, T.,Zhiheng, D.,Jiakun, T.,Liying, Z.,Jia-Bin, L.,Man, P.,Liu, L. (deposition date: 2022-09-02, release date: 2023-04-12, Last modification date: 2024-07-03) |
Primary citation | Ai, H.S.,Tong, Z.,Deng, Z.,Tian, J.,Zhang, L.,Sun, M.,Du, Y.,Xu, Z.,Shi, Q.,Liang, L.,Zheng, Q.,Li, J.B.,Pan, M.,Liu, L. Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination. Chem, 2023 Cited by DOI: 10.1016/j.chempr.2023.01.012PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.87 Å) |
Structure validation
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