8X7K

Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by activity-based chemical trapping strategy (adjacent H2AK13/15 dual-monoubiquitination)

Summary for 8X7K

Entry DOI	10.2210/pdb8x7k/pdb
EMDB information	38101
Descriptor	Histone H3.2, ZINC ION, Histone H4, ... (10 entities in total)
Functional Keywords	rnf168, nucleosome, h2ak13/15 ubiquitination, nuclear protein, nuclear protein-dna complex, nuclear protein/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	203806.77
Authors	Ai, H.S.,Tong, Z.B.,Deng, Z.H.,Pan, M.,Liu, L. (deposition date: 2023-11-24, release date: 2024-08-07)
Primary citation	Ai, H.,Tong, Z.,Deng, Z.,Shi, Q.,Tao, S.,Liang, J.,Sun, M.,Wu, X.,Zheng, Q.,Liang, L.,Li, J.B.,Gao, S.,Tian, C.,Liu, L.,Pan, M. Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 Biorxiv, 2024 Cited by DOI: 10.1101/2024.01.02.573964 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.27 Å)

Structure validation