7JO9

1:1 cGAS-nucleosome complex

Summary for 7JO9

Entry DOI	10.2210/pdb7jo9/pdb
EMDB information	22408
Descriptor	Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total)
Functional Keywords	cgas, nucleosome, cyclic gmp-amp synthase, dna binding protein-dna-transferase complex, dna binding protein/dna/transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	11
Total formula weight	243022.66
Authors	Boyer, J.A.,Spangler, C.J.,Strauss, J.D.,Cesmat, A.P.,Liu, P.,McGinty, R.K.,Zhang, Q. (deposition date: 2020-08-06, release date: 2020-09-16, Last modification date: 2024-03-06)
Primary citation	Boyer, J.A.,Spangler, C.J.,Strauss, J.D.,Cesmat, A.P.,Liu, P.,McGinty, R.K.,Zhang, Q. Structural basis of nucleosome-dependent cGAS inhibition. Science, 370:450-454, 2020 Cited by PubMed: 32913000 DOI: 10.1126/science.abd0609 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation