6GWS
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![BU of 6gws by Molmil](/molmil-images/mine/6gws) | Crystal structure of human PCNA in complex with three p15 peptides | 分子名称: | PCNA-associated factor, Proliferating cell nuclear antigen | 著者 | De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A. | 登録日 | 2018-06-25 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
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6GIS
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![BU of 6gis by Molmil](/molmil-images/mine/6gis) | Structural basis of human clamp sliding on DNA | 分子名称: | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen | 著者 | De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. | 登録日 | 2018-05-15 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Structural basis of human PCNA sliding on DNA. Nat Commun, 8, 2017
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3WGW
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![BU of 3wgw by Molmil](/molmil-images/mine/3wgw) | Structure of PCNA bound to a small molecule inhibitor | 分子名称: | 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION | 著者 | Hashimoto, H. | 登録日 | 2013-08-12 | 公開日 | 2014-02-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
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8P9O
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![BU of 8p9o by Molmil](/molmil-images/mine/8p9o) | |
8Q7I
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![BU of 8q7i by Molmil](/molmil-images/mine/8q7i) | |
8PPU
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![BU of 8ppu by Molmil](/molmil-images/mine/8ppu) | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
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8PPV
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![BU of 8ppv by Molmil](/molmil-images/mine/8ppv) | Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches | 分子名称: | DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
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8PPT
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![BU of 8ppt by Molmil](/molmil-images/mine/8ppt) | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
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3LX1
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![BU of 3lx1 by Molmil](/molmil-images/mine/3lx1) | |
3V61
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![BU of 3v61 by Molmil](/molmil-images/mine/3v61) | Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 | 分子名称: | BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... | 著者 | Armstrong, A.A, Mohideen, F, Lima, C.D. | 登録日 | 2011-12-18 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
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3P91
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![BU of 3p91 by Molmil](/molmil-images/mine/3p91) | |
3V60
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![BU of 3v60 by Molmil](/molmil-images/mine/3v60) | |
3VKX
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![BU of 3vkx by Molmil](/molmil-images/mine/3vkx) | Structure of PCNA | 分子名称: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | 著者 | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | 登録日 | 2011-11-26 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
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3P87
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![BU of 3p87 by Molmil](/molmil-images/mine/3p87) | Structure of human PCNA bound to RNASEH2B PIP box peptide | 分子名称: | Proliferating cell nuclear antigen, Ribonuclease H2 subunit B | 著者 | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | 登録日 | 2010-10-13 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
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3P83
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![BU of 3p83 by Molmil](/molmil-images/mine/3p83) | Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus. | 分子名称: | DNA polymerase sliding clamp, Ribonuclease HII | 著者 | Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. | 登録日 | 2010-10-13 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
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8F5Q
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![BU of 8f5q by Molmil](/molmil-images/mine/8f5q) | Crystal structure of human PCNA in complex with the PIP box of FBH1 | 分子名称: | F-box DNA helicase 1, Proliferating cell nuclear antigen | 著者 | Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T. | 登録日 | 2022-11-15 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insight into the PCNA-binding mode of FBH1. Structure, 31, 2023
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2IZO
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![BU of 2izo by Molmil](/molmil-images/mine/2izo) | Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex | 分子名称: | DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ... | 著者 | Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H. | 登録日 | 2006-07-25 | 公開日 | 2006-09-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity. Nucleic Acids Res., 34, 2006
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3GPM
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![BU of 3gpm by Molmil](/molmil-images/mine/3gpm) | Structure of the trimeric form of the E113G PCNA mutant protein | 分子名称: | Proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | 登録日 | 2009-03-23 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
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2IX2
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![BU of 2ix2 by Molmil](/molmil-images/mine/2ix2) | Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus | 分子名称: | DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C | 著者 | Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H. | 登録日 | 2006-07-05 | 公開日 | 2006-10-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus. Acta Crystallogr.,Sect.F, 62, 2006
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6J0J
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![BU of 6j0j by Molmil](/molmil-images/mine/6j0j) | |
3HI8
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![BU of 3hi8 by Molmil](/molmil-images/mine/3hi8) | Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii | 分子名称: | Proliferating cell nuclear antigen PcnA | 著者 | Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. | 登録日 | 2009-05-19 | 公開日 | 2009-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | 主引用文献 | Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
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5DA7
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![BU of 5da7 by Molmil](/molmil-images/mine/5da7) | monomeric PCNA bound to a small protein inhibitor | 分子名称: | DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... | 著者 | Ladner, J.E, Altieri, A.S, Kelman, Z. | 登録日 | 2015-08-19 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
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3IFV
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![BU of 3ifv by Molmil](/molmil-images/mine/3ifv) | Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen | 分子名称: | PCNA, SODIUM ION | 著者 | Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. | 登録日 | 2009-07-26 | 公開日 | 2009-09-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Bmc Struct.Biol., 9, 2009
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2IO4
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![BU of 2io4 by Molmil](/molmil-images/mine/2io4) | Crystal structure of PCNA12 dimer from Sulfolobus solfataricus. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ... | 著者 | Hlinkova, V, Ling, H. | 登録日 | 2006-10-09 | 公開日 | 2008-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
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8GLA
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![BU of 8gla by Molmil](/molmil-images/mine/8gla) | |