8PPT

Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch

Summary for 8PPT

• Entry DOI: 10.2210/pdb8ppt/pdb
• EMDB information: 17815
• Descriptor: DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), ... (7 entities in total)
• Functional Keywords: polymerase, dna, replication, pold, archaea, editing, proofreading, exonuclease, nuclease, dna binding protein
• Biological source: Pyrococcus abyssi GE5; More
• Total number of polymer chains: 7
• Total formula weight: 320374.65

Authors

Betancurt-Anzola, L.,Martinez-Carranza, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L. (deposition date: 2023-07-10, release date: 2023-12-20, Last modification date: 2023-12-27)

• Primary citation: Betancurt-Anzola, L.,Martinez-Carranza, M.,Delarue, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L.; Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.; Nat Commun, 14:8306-8306, 2023; PubMed: 38097591; DOI: 10.1038/s41467-023-44125-x

Experimental method

ELECTRON MICROSCOPY (2.9 Å)