8PPU
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches
Summary for 8PPU
Entry DOI | 10.2210/pdb8ppu/pdb |
EMDB information | 17816 |
Descriptor | DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... (7 entities in total) |
Functional Keywords | polymerase, dna, replication, pold, archaea, editing, proofreading, exonuclease, nuclease, dna binding protein |
Biological source | Pyrococcus abyssi GE5 More |
Total number of polymer chains | 7 |
Total formula weight | 321343.53 |
Authors | Betancurt-Anzola, L.,Martinez-Carranza, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L. (deposition date: 2023-07-10, release date: 2023-12-20, Last modification date: 2023-12-27) |
Primary citation | Betancurt-Anzola, L.,Martinez-Carranza, M.,Delarue, M.,Zatopek, K.M.,Gardner, A.F.,Sauguet, L. Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14:8306-8306, 2023 Cited by PubMed: 38097591DOI: 10.1038/s41467-023-44125-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.02 Å) |
Structure validation
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