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PDB: 249 件

8IIB
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BU of 8iib by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546)
分子名称: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
著者Fang, X, Lu, G, Hou, C, Gong, P.
登録日2023-02-24
公開日2023-06-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
4IKA
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BU of 4ika by Molmil
Crystal structure of EV71 3Dpol-VPg
分子名称: 3Dpol, NICKEL (II) ION, VPg
著者Chen, C, Wang, Y.X, Lou, Z.Y.
登録日2012-12-25
公開日2013-09-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation
J.Virol., 87, 2013
2UUW
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BU of 2uuw by Molmil
2.75 angstrom structure of the D347G D348G mutant structure of Sapporo Virus RdRp Polymerase
分子名称: RNA-DIRECTED RNA POLYMERASE
著者Fullerton, S, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J.
登録日2007-03-07
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The 2.76 Angstrom Resolution Structure of the D347G D348G Mutant Structure of Sapporo Virus Rdrp Polymerase
To be Published
3SFG
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BU of 3sfg by Molmil
crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU)
分子名称: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ...
著者Kim, K.H, Alam, I.
登録日2011-06-13
公開日2012-05-09
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
2WK4
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BU of 2wk4 by Molmil
Dimeric structure of D347G D348G mutant of the sapporovirus RNA dependent RNA polymerase
分子名称: GLYCEROL, PROTEASE-POLYMERASE P70
著者Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P.A, Rohayem, J.
登録日2009-06-05
公開日2010-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Dimeric Structure of D347G D348G Mutant of the Sapporovirus Sapporovirus RNA Dependent RNA Polymerase
To be Published
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
分子名称: MAGNESIUM ION, RNA Primer, RNA Template, ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2016-05-13
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
4IQX
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BU of 4iqx by Molmil
Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
分子名称: 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3')
著者Ferrer-Orta, C, Verdaguer, N, Agudo, R, Perez-Luque, R.
登録日2013-01-14
公開日2013-02-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
1KHW
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BU of 1khw by Molmil
Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N.
登録日2001-12-01
公開日2002-01-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
J.Biol.Chem., 277, 2002
5I61
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BU of 5i61 by Molmil
Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus
分子名称: Potential RNA-dependent RNA polymerase
著者Collier, A.M, Guo, Y.R, Tao, Y.J.
登録日2016-02-15
公開日2016-03-16
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
1HI0
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BU of 1hi0 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex
分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2000-12-31
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
3H5Y
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BU of 3h5y by Molmil
Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
分子名称: 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ...
著者Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
登録日2009-04-22
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
3H5X
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BU of 3h5x by Molmil
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
分子名称: 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ...
著者Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
登録日2009-04-22
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
4K4Y
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BU of 4k4y by Molmil
Coxsackievirus B3 polymerase elongation complex (r2+1_form)
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*(DOC))-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4ZP8
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BU of 4zp8 by Molmil
Coxsackievirus B3 Polymerase - F364L mutant
分子名称: RNA-dependent RNA polymerase
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.894 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPA
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BU of 4zpa by Molmil
Coxsackievirus B3 Polymerase - F364Y mutant
分子名称: RNA-directed RNA polymerase, SULFATE ION
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.665 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP6
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BU of 4zp6 by Molmil
Coxsackievirus B3 Polymerase - F364A mutant
分子名称: Genome polyprotein, SULFATE ION
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP9
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BU of 4zp9 by Molmil
Coxsackievirus B3 Polymerase - F364I mutant
分子名称: RNA-dependent RNA polymerase
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
3BSO
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BU of 3bso by Molmil
Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA
分子名称: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Zamyatkin, D.F, Ng, K.K.S.
登録日2007-12-26
公開日2008-01-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
J.Biol.Chem., 283, 2008
1HHT
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BU of 1hht by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template
分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2000-12-28
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HHS
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BU of 1hhs by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2000-12-28
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
3BSN
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BU of 3bsn by Molmil
Norwalk Virus polymerase bound to 5-nitrocytidine triphosphate and primer-template RNA
分子名称: 5-nitrocytidine 5'-(tetrahydrogen triphosphate), GLYCEROL, MANGANESE (II) ION, ...
著者Zamyatkin, D.F, Ng, K.K.S.
登録日2007-12-26
公開日2008-01-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
J.Biol.Chem., 283, 2008
1HI1
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BU of 1hi1 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-01
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI8
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BU of 1hi8 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6
分子名称: MAGNESIUM ION, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-03
公開日2001-03-27
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
3CDU
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BU of 3cdu by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
登録日2008-02-27
公開日2008-07-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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BU of 3cdw by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
登録日2008-02-27
公開日2008-07-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008

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