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PDB: 392 件

5KO2
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BU of 5ko2 by Molmil
Mouse pgp 34 linker deleted mutant Hg derivative
分子名称: MERCURY (II) ION, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-06-29
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KOY
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BU of 5koy by Molmil
Mouse pgp 34 linker deleted bound with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-01
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPD
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BU of 5kpd by Molmil
Mouse pgp 34 linker deleted double EQ mutant
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-03
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPI
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BU of 5kpi by Molmil
Mouse native PGP
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-04
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPJ
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BU of 5kpj by Molmil
Mouse pgp methylated protein
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-04
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5L22
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BU of 5l22 by Molmil
PrtD T1SS ABC transporter
分子名称: ABC transporter (HlyB subfamily), ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Morgan, J.L.W, Zimmer, J.
登録日2016-07-30
公開日2017-03-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of a Type-1 Secretion System ABC Transporter.
Structure, 25, 2017
5TV4
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BU of 5tv4 by Molmil
3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc
分子名称: 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ...
著者Mi, W, Walz, T, Liao, M.
登録日2016-11-08
公開日2017-09-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5U1D
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BU of 5u1d by Molmil
Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, TAP transporter inhibitor ICP47
著者Oldham, M.L, Chen, J, Grigorieff, N.
登録日2016-11-28
公開日2017-01-11
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structure of the transporter associated with antigen processing trapped by herpes simplex virus.
Elife, 5, 2016
8CHB
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BU of 8chb by Molmil
Inward-facing conformation of the ABC transporter BmrA C436S/A582C cross-linked mutant
分子名称: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
著者Di Cesare, M, Kaplan, E, Hanssen, E, Valimehr, S, Orelle, C, Jault, J.M.
登録日2023-02-07
公開日2023-12-20
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
8F4B
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BU of 8f4b by Molmil
Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1)
分子名称: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1
著者Pietz, H.L, Chen, J.
登録日2022-11-10
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation.
Proc.Natl.Acad.Sci.USA, 120, 2023
5TWV
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BU of 5twv by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
著者Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L.
登録日2016-11-14
公開日2017-01-25
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Elife, 6, 2017
7SGR
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BU of 7sgr by Molmil
Structure of hemolysin A secretion system HlyB/D complex
分子名称: Alpha-hemolysin translocation ATP-binding protein HlyB, Membrane fusion protein (MFP) family protein,Hemolysin secretion protein D, chromosomal, ...
著者Zhao, H, Chen, J.
登録日2021-10-07
公開日2022-09-14
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
Cell, 185, 2022
7O9W
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BU of 7o9w by Molmil
Encequidar-bound human P-glycoprotein in complex with UIC2-Fab
分子名称: Multidrug resistance protein 1, UIC2 Fab-fragment heavy chain, UIC2 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2021-04-17
公開日2022-01-12
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.
J.Med.Chem., 65, 2022
5UAR
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BU of 5uar by Molmil
Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (CFTR) from zebrafish
分子名称: Cystic fibrosis transmembrane conductance regulator, DECANE
著者Zhang, Z, Chen, J.
登録日2016-12-19
公開日2017-01-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator.
Cell, 167, 2016
5UJ9
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BU of 5uj9 by Molmil
Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1)
分子名称: bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1
著者Johnson, Z.L, Chen, J.
登録日2017-01-17
公開日2017-02-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1.
Cell, 168, 2017
7OCY
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BU of 7ocy by Molmil
Enterococcus faecalis EfrCD in complex with a nanobody
分子名称: ABC transporter ATP-binding protein, Nanobody
著者Ehrenbolger, K, Hutter, C.A.J, Meier, G, Seeger, M.A, Barandun, J.
登録日2021-04-28
公開日2022-05-18
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Deep mutational scan of a drug efflux pump reveals its structure-function landscape.
Nat.Chem.Biol., 19, 2023
8DCK
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BU of 8dck by Molmil
Structure of hemolysin A secretion system HlyB/D complex, ATP-bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein HlyB, MAGNESIUM ION, ...
著者Zhao, H, Chen, J.
登録日2022-06-16
公開日2022-09-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
Cell, 185, 2022
7SVR
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BU of 7svr by Molmil
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
分子名称: Cystic fibrosis transmembrane conductance regulator, Lumacaftor
著者Fiedorczuk, K, Chen, J.
登録日2021-11-19
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SV7
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BU of 7sv7 by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SVD
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BU of 7svd by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7T56
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BU of 7t56 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing intermediate conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T54
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BU of 7t54 by Molmil
Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T57
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BU of 7t57 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T55
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BU of 7t55 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing wide conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
8FWK
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BU of 8fwk by Molmil
CryoEM structure of Human ABCB6 Transporter
分子名称: ATP-binding cassette sub-family B member 6
著者Shaik, M.M, Myasnikov, A.
登録日2023-01-22
公開日2023-02-08
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献CryoEM structure of Human ABCB6 Transporter
To Be Published

223532

件を2024-08-07に公開中

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