8CHB

Inward-facing conformation of the ABC transporter BmrA C436S/A582C cross-linked mutant

Summary for 8CHB

• Entry DOI: 10.2210/pdb8chb/pdb
• Related: 8QOE
• EMDB information: 16659
• Descriptor: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA (1 entity in total)
• Functional Keywords: abc transporter, drug efflux pump, homodimer, membrane protein, antibiotic resistance
• Biological source: Bacillus subtilis
• Total number of polymer chains: 2
• Total formula weight: 132681.67

Authors

Di Cesare, M.,Kaplan, E.,Hanssen, E.,Valimehr, S.,Orelle, C.,Jault, J.M. (deposition date: 2023-02-07, release date: 2023-12-20, Last modification date: 2024-01-24)

• Primary citation: Di Cesare, M.,Kaplan, E.,Rendon, J.,Gerbaud, G.,Valimehr, S.,Gobet, A.,Ngo, T.T.,Chaptal, V.,Falson, P.,Martinho, M.,Dorlet, P.,Hanssen, E.,Jault, J.M.,Orelle, C.; The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.; J.Biol.Chem., 300:105546-105546, 2023; PubMed: 38072053; DOI: 10.1016/j.jbc.2023.105546

Experimental method

ELECTRON MICROSCOPY (3.14 Å)