5TWV

Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide

Summary for 5TWV

• Entry DOI: 10.2210/pdb5twv/pdb
• EMDB information: 8470
• Descriptor: ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: katp, kir6.2, sur1, potassium channel, transport protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 8
• Total formula weight: 889933.66

Authors

Martin, G.M.,Yoshioka, C.,Chen, J.Z.,Shyng, S.L. (deposition date: 2016-11-14, release date: 2017-01-25, Last modification date: 2019-12-25)

• Primary citation: Martin, G.M.,Yoshioka, C.,Rex, E.A.,Fay, J.F.,Xie, Q.,Whorton, M.R.,Chen, J.Z.,Shyng, S.L.; Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.; Elife, 6:-, 2017; PubMed: 28092267; DOI: 10.7554/eLife.24149

Experimental method

ELECTRON MICROSCOPY (6.3 Å)