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PDB: 289 件

1QGR
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BU of 1qgr by Molmil
STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH)
分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT)
著者Cingolani, G, Petosa, C, Weis, K, Muller, C.W.
登録日1999-05-04
公開日1999-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
1QGK
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BU of 1qgk by Molmil
STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA
分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT)
著者Cingolani, G, Petosa, C, Weis, K, Muller, C.W.
登録日1999-04-29
公開日1999-05-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
7LEU
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BU of 7leu by Molmil
Structure of importin a2 bound to p65-NLS
分子名称: Importin subunit alpha-1, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LET
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BU of 7let by Molmil
Structure of importin a2 bound to the p50- and p65-NLSs
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-14
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LFC
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BU of 7lfc by Molmil
Structure of importin a3 bound to p50 NLS
分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-16
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LF4
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BU of 7lf4 by Molmil
Structure of importin a3 bound to the p50- and p65-NLSs
分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7M60
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BU of 7m60 by Molmil
Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1
著者De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M.
登録日2021-03-25
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
1QZ7
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BU of 1qz7 by Molmil
Beta-catenin binding domain of Axin in complex with beta-catenin
分子名称: Axin, Beta-catenin
著者Xing, Y, Clements, W.K, Kimelman, D, Xu, W.
登録日2003-09-15
公開日2003-11-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex
GENES DEV., 17, 2003
7NSC
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BU of 7nsc by Molmil
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
分子名称: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ...
著者Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
1T08
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BU of 1t08 by Molmil
Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3
分子名称: Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1
著者Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I.
登録日2004-04-07
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
Mol.Cell, 15, 2004
1TH1
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BU of 1th1 by Molmil
Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment
分子名称: Adenomatous polyposis coli protein, Beta-catenin
著者Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W.
登録日2004-05-31
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function.
Mol.Cell, 15, 2004
4XZR
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BU of 4xzr by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-04
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
4YJE
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BU of 4yje by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A1
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
4YJL
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BU of 4yjl by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A2
分子名称: 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
4YI0
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BU of 4yi0 by Molmil
Structure of mouse importin a1 bound to Pom121NLS
分子名称: Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-27
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
4YK6
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BU of 4yk6 by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A4
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-04
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
4ZDU
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BU of 4zdu by Molmil
Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
分子名称: Importin subunit alpha-1, Peptide from Nucleoprotein
著者Nakada, R, Hirano, H, Matsuura, Y.
登録日2015-04-19
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Sci Rep, 5, 2015
6BVZ
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BU of 6bvz by Molmil
Importin alpha 3 in cargo free state
分子名称: Importin subunit alpha-3
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW9
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BU of 6bw9 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWA
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BU of 6bwa by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BVT
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BU of 6bvt by Molmil
Importin alpha 1 in cargo free state
分子名称: Importin subunit alpha-1
著者Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-13
公開日2018-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW0
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BU of 6bw0 by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 1
分子名称: Importin subunit alpha-1, Protein W
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW1
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BU of 6bw1 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 1
分子名称: Importin subunit alpha-1, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018

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