7LET

Structure of importin a2 bound to the p50- and p65-NLSs

Summary for 7LET

• Entry DOI: 10.2210/pdb7let/pdb
• Related: 7LEQ
• Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65, ... (4 entities in total)
• Functional Keywords: nuclear import, importin alpha, nls, nf-kb, p50, p65, protein transport
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 51066.58

Authors

Florio, T.J.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2021-01-15, release date: 2022-01-19, Last modification date: 2023-10-18)

• Primary citation: Florio, T.J.,Lokareddy, R.K.,Yeggoni, D.P.,Sankhala, R.S.,Ott, C.A.,Gillilan, R.E.,Cingolani, G.; Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.; Nat Commun, 13:1207-1207, 2022; PubMed: 35260573; DOI: 10.1038/s41467-022-28846-z

Experimental method

X-RAY DIFFRACTION (2.4 Å)