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7LET

Structure of importin a2 bound to the p50- and p65-NLSs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
Importin subunit alpha-1polymer42846386.11UniProt (P52293)
Pfam (PF01749)
Pfam (PF00514)
Pfam (PF16186)
Mus musculus (Mouse)Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha
2B
(B)
Nuclear factor NF-kappa-B p105 subunitpolymer141790.11UniProt (P19838)Homo sapiensDNA-binding factor KBF1,EBP-1,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
3C
(C)
Transcription factor p65polymer222890.41UniProt (Q04206)Homo sapiensNuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
4D, E
(E, B)
waterwater18.032Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight51066.6
All*Total formula weight51066.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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