6SQO
| Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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7O81
| Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7O7Z
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7O7Y
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7OJX
| E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis | 分子名称: | 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), E3 ubiquitin-protein ligase RNF38, Polyubiquitin-B, ... | 著者 | Majorek, K.A, Nakasone, M.A, Huang, D.T. | 登録日 | 2021-05-17 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nat.Chem.Biol., 18, 2022
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7O80
| Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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6QTZ
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6R6G
| Structure of XBP1u-paused ribosome nascent chain complex with SRP. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | 登録日 | 2019-03-27 | 公開日 | 2019-07-10 | 最終更新日 | 2019-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6R6P
| Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | 分子名称: | 18S rRNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2019-03-27 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6SGC
| Rabbit 80S ribosome stalled on a poly(A) tail | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2019-08-03 | 公開日 | 2019-12-04 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
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6R7Q
| Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | 登録日 | 2019-03-29 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6RBE
| State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. | 登録日 | 2019-04-10 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
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6SQS
| Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | 分子名称: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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6R5Q
| Structure of XBP1u-paused ribosome nascent chain complex (post-state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2019-03-25 | 公開日 | 2019-07-10 | 最終更新日 | 2019-10-30 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6SV4
| The cryo-EM structure of SDD1-stalled collided trisome. | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R. | 登録日 | 2019-09-17 | 公開日 | 2020-03-04 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nat.Struct.Mol.Biol., 27, 2020
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6SNT
| Yeast 80S ribosome stalled on SDD1 mRNA. | 分子名称: | 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S10-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R. | 登録日 | 2019-08-27 | 公開日 | 2020-03-04 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nat.Struct.Mol.Biol., 27, 2020
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6SQR
| Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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7NWI
| Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7NWG
| Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7NWH
| Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7ONI
| Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* | 分子名称: | Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ... | 著者 | Kostrhon, S.P, prabu, J.R, Schulman, B.A. | 登録日 | 2021-05-25 | 公開日 | 2021-09-15 | 最終更新日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nat.Chem.Biol., 17, 2021
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6RI5
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6T7I
| Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | 登録日 | 2019-10-22 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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7P47
| Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic | 分子名称: | E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... | 著者 | Lascorz, J, Varejao, N, Reverter, D. | 登録日 | 2021-07-09 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.314 Å) | 主引用文献 | Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. Nat Commun, 12, 2021
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1ZGU
| Solution structure of the human Mms2-Ubiquitin complex | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2 | 著者 | Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L. | 登録日 | 2005-04-22 | 公開日 | 2006-04-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2. J.Biomol.Nmr, 34, 2006
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