7P47
Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic
Summary for 7P47
Entry DOI | 10.2210/pdb7p47/pdb |
Descriptor | Structural maintenance of chromosomes protein 5, SUMO-conjugating enzyme UBC9, E3 SUMO-protein ligase MMS21, ... (5 entities in total) |
Functional Keywords | sumo e3 ligase activity, dna repair, ligase |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 5 |
Total formula weight | 80711.56 |
Authors | Lascorz, J.,Varejao, N.,Reverter, D. (deposition date: 2021-07-09, release date: 2021-11-24, Last modification date: 2024-01-31) |
Primary citation | Varejao, N.,Lascorz, J.,Codina-Fabra, J.,Belli, G.,Borras-Gas, H.,Torres-Rosell, J.,Reverter, D. Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. Nat Commun, 12:7013-7013, 2021 Cited by PubMed: 34853311DOI: 10.1038/s41467-021-27301-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.314 Å) |
Structure validation
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