4UUZ
| MCM2-histone complex | 分子名称: | DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4 | 著者 | Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F. | 登録日 | 2014-08-01 | 公開日 | 2015-02-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork. Nucleic Acids Res., 43, 2015
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8B9D
| Human replisome bound by Pol Alpha | 分子名称: | Cell division control protein 45 homolog, Claspin, DNA Molecule, ... | 著者 | Jones, M.L, Yeeles, J.T.P. | 登録日 | 2022-10-05 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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5JA4
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8YJM
| Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera | 分子名称: | DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2B 1/2/3/4/6,Histone H2A type 1-D, ... | 著者 | Gan, S.L, Yang, W.S, Xu, R.M. | 登録日 | 2024-03-02 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2. Sci China Life Sci, 67, 2024
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8YJF
| Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and an H2A-H2B dimer | 分子名称: | DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2A type 1-D, ... | 著者 | Gan, S.L, Yang, W.S, Xu, R.M. | 登録日 | 2024-03-01 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2. Sci China Life Sci, 67, 2024
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7PLO
| H. sapiens replisome-CUL2/LRR1 complex | 分子名称: | Cell division control protein 45 homolog, Claspin, Cullin-2, ... | 著者 | Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M. | 登録日 | 2021-09-01 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
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7PFO
| Core human replisome | 分子名称: | Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ... | 著者 | Jones, M.J, Yeeles, J.T.P. | 登録日 | 2021-08-11 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of a human replisome shows the organisation and interactions of a DNA replication machine. Embo J., 40, 2021
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7W1Y
| Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ... | 著者 | Li, J, Dong, J, Dang, S, Zhai, Y. | 登録日 | 2021-11-21 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | The human pre-replication complex is an open complex. Cell, 186, 2023
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7W68
| human single hexameric Mcm2-7 complex | 分子名称: | DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... | 著者 | Xu, N.N, Lin, Q.P, Liu, C.D, Tian, H.L, Xiang, Y, Zhu, G. | 登録日 | 2021-12-01 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | human single hexameric Mcm2-7 complex To Be Published
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7CJ0
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7CIZ
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6XTY
| CryoEM structure of human CMG bound to AND-1 (CMGA) | 分子名称: | Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... | 著者 | Rzechorzek, N.J, Pellegrini, L, Chirgadze, D.Y, Hardwick, S.W. | 登録日 | 2020-01-16 | 公開日 | 2020-05-27 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (6.77 Å) | 主引用文献 | CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes. Nucleic Acids Res., 48, 2020
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6YA7
| Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, DNA replication licensing factor MCM2, ... | 著者 | Dick, S.D, Cherepanov, P. | 登録日 | 2020-03-11 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase. Structure, 28, 2020
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6XTX
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5BO0
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5BNV
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5BNX
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5C3I
| Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 | 分子名称: | DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ... | 著者 | Wang, H, Wang, M, Yang, N, Xu, R.M. | 登録日 | 2015-06-17 | 公開日 | 2015-07-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Protein Cell, 6, 2015
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8S0B
| H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (45-mer), DNA replication licensing factor MCM2, ... | 著者 | Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A. | 登録日 | 2024-02-13 | 公開日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | MCM Double Hexamer Loading Visualised with Human Proteins Nature, 2024
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9CAQ
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8W0I
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8W0G
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8W0E
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8W0F
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8S0D
| H. sapiens MCM bound to double stranded DNA and ORC1-6 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (58-mer), DNA replication licensing factor MCM2, ... | 著者 | Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A. | 登録日 | 2024-02-13 | 公開日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | MCM Double Hexamer Loading Visualised with Human Proteins Nature, 2024
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