6XTX

CryoEM structure of human CMG bound to ATPgammaS and DNA

Summary for 6XTX

Entry DOI	10.2210/pdb6xtx/pdb
EMDB information	10619
Descriptor	DNA replication licensing factor MCM2, DNA replication complex GINS protein SLD5, Cell division control protein 45 homolog, ... (16 entities in total)
Functional Keywords	cmg, helicase, atpase, replisome, replication
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	742894.70
Authors	Rzechorzek, N.J.,Pellegrini, L. (deposition date: 2020-01-16, release date: 2020-05-27, Last modification date: 2020-07-15)
Primary citation	Rzechorzek, N.J.,Hardwick, S.W.,Jatikusumo, V.A.,Chirgadze, D.Y.,Pellegrini, L. CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes. Nucleic Acids Res., 48:6980-6995, 2020 Cited by PubMed: 32453425 DOI: 10.1093/nar/gkaa429 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.29 Å)

Structure validation