8YJM

Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera

Summary for 8YJM

• Entry DOI: 10.2210/pdb8yjm/pdb
• Related: 8YJF
• Descriptor: FACT complex subunit SPT16, DNA replication licensing factor MCM2, Histone H3.1, ... (5 entities in total)
• Functional Keywords: dna replication, histone chaperone, fact, parental histones transfer, replication
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 116121.39

Authors

Gan, S.L.,Yang, W.S.,Xu, R.M. (deposition date: 2024-03-02, release date: 2024-03-20, Last modification date: 2024-06-19)

• Primary citation: Gan, S.,Yang, W.S.,Wei, L.,Zhang, Z.,Xu, R.M.; Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.; Sci China Life Sci, 67:1305-1307, 2024; PubMed: 38478295; DOI: 10.1007/s11427-024-2560-8

Experimental method

X-RAY DIFFRACTION (4.15 Å)