6YA7
Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate
Summary for 6YA7
Entry DOI | 10.2210/pdb6ya7/pdb |
Descriptor | Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, DNA replication licensing factor MCM2, ... (6 entities in total) |
Functional Keywords | kinase, cdc7, dbf4, cell cycle, bivalent substrate, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 59509.41 |
Authors | Dick, S.D.,Cherepanov, P. (deposition date: 2020-03-11, release date: 2020-05-27, Last modification date: 2024-01-24) |
Primary citation | Dick, S.D.,Federico, S.,Hughes, S.M.,Pye, V.E.,O'Reilly, N.,Cherepanov, P. Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase. Structure, 28:954-962.e4, 2020 Cited by PubMed: 32521228DOI: 10.1016/j.str.2020.05.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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