7W1Y

Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA)

This is a non-PDB format compatible entry.

Summary for 7W1Y

• Entry DOI: 10.2210/pdb7w1y/pdb
• EMDB information: 32258
• Descriptor: DNA replication licensing factor MCM2, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (12 entities in total)
• Functional Keywords: replication, cell cycle-dna complex, cell cycle/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 1140056.77

Authors

Li, J.,Dong, J.,Dang, S.,Zhai, Y. (deposition date: 2021-11-21, release date: 2023-02-08)

• Primary citation: Li, J.,Dong, J.,Wang, W.,Yu, D.,Fan, X.,Hui, Y.C.,Lee, C.S.K.,Lam, W.H.,Alary, N.,Yang, Y.,Zhang, Y.,Zhao, Q.,Chen, C.L.,Tye, B.K.,Dang, S.,Zhai, Y.; The human pre-replication complex is an open complex.; Cell, 186:98-111.e21, 2023; PubMed: 36608662; DOI: 10.1016/j.cell.2022.12.008

Experimental method

ELECTRON MICROSCOPY (2.59 Å)