7W1Y
Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | 2, A | DNA replication licensing factor MCM2 | polymer | 904 | 102034.1 | 2 | UniProt (P49736) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) In PDB | Homo sapiens (human) | Minichromosome maintenance protein 2 homolog,Nuclear protein BM28 |
| 2 | 3, B | Isoform 2 of DNA replication licensing factor MCM3 | polymer | 853 | 96043.3 | 2 | UniProt (P25205) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) In PDB | Homo sapiens (human) | DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102 |
| 3 | 4, C | DNA replication licensing factor MCM4 | polymer | 863 | 96684.9 | 2 | UniProt (P33991) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) In PDB | Homo sapiens (human) | CDC21 homolog,P1-CDC21 |
| 4 | 5, D | DNA replication licensing factor MCM5 | polymer | 734 | 82406.6 | 2 | UniProt (P33992) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) In PDB | Homo sapiens (human) | CDC46 homolog,P1-CDC46 |
| 5 | 6, E | DNA replication licensing factor MCM6 | polymer | 821 | 93010.3 | 2 | UniProt (Q14566) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263) In PDB | Homo sapiens (human) | p105MCM |
| 6 | 7, F | DNA replication licensing factor MCM7 | polymer | 719 | 81411.9 | 2 | UniProt (P33993) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) In PDB | Homo sapiens (human) | CDC47 homolog,P1.1-MCM3 |
| 7 | O | DNA (49-MER) | polymer | 49 | 15302.2 | 1 | Homo sapiens (Human) | ||
| 8 | S | DNA (49-MER) | polymer | 49 | 14860.5 | 1 | Homo sapiens (Human) | ||
| 9 | 7, A, C, D, 2... | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 10 | 6, 7, A, B, C... | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 11 | 7, A, B, C, 2... | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
| 12 | 6, D, E, 5 | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 1133344.8 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 6712.0 | |
| All* | Total formula weight | 1140056.8 |
