8YJF

Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and an H2A-H2B dimer

Summary for 8YJF

• Entry DOI: 10.2210/pdb8yjf/pdb
• Related: 4z2m
• Descriptor: FACT complex subunit SPT16, DNA replication licensing factor MCM2, Histone H3.1, ... (6 entities in total)
• Functional Keywords: dna replication, histone chaperone, fact, mcm2, parental histones transfer, replication
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 121374.93

Authors

Gan, S.L.,Yang, W.S.,Xu, R.M. (deposition date: 2024-03-01, release date: 2024-03-20, Last modification date: 2024-03-27)

• Primary citation: Gan, S.,Yang, W.S.,Wei, L.,Zhang, Z.,Xu, R.M.; Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.; Sci China Life Sci, 2024; PubMed: 38478295; DOI: 10.1007/s11427-024-2560-8

Experimental method

X-RAY DIFFRACTION (4.4 Å)