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PDB: 18 件

6YA7
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Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, DNA replication licensing factor MCM2, ...
著者Dick, S.D, Cherepanov, P.
登録日2020-03-11
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
7CIZ
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Crystal structure of DNAJC9 HBD helix2 in complex with H3.3-H4 dimer and MCM2 HBD
分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, Histone H3.3, ...
著者Bao, H, Huang, H.
登録日2020-07-08
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
5BNX
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Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.3-H4 dimer
分子名称: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.3, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
5JA4
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Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA replication licensing factor MCM2, GLYCEROL, ...
著者Huang, H, Patel, D.
登録日2016-04-11
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex.
Nature, 534, 2016
7CJ0
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Crystal structure of DNAJC9 HBD in complex with H3.3-H4 dimer and MCM2 HBD
分子名称: DNA replication licensing factor MCM2, DnaJ homolog subfamily C member 9, GLYCEROL, ...
著者Bao, H, Huang, H.
登録日2020-07-09
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.
Mol.Cell, 81, 2021
7W1Y
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Human MCM double hexamer bound to natural DNA duplex (polyAT/polyTA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (49-MER), ...
著者Li, J, Dong, J, Dang, S, Zhai, Y.
登録日2021-11-21
公開日2023-02-08
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献The human pre-replication complex is an open complex.
Cell, 186, 2023
5BNV
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Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer
分子名称: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
7PLO
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H. sapiens replisome-CUL2/LRR1 complex
分子名称: Cell division control protein 45 homolog, Claspin, Cullin-2, ...
著者Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M.
登録日2021-09-01
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
4UUZ
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MCM2-histone complex
分子名称: DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4
著者Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F.
登録日2014-08-01
公開日2015-02-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork.
Nucleic Acids Res., 43, 2015
5BO0
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BU of 5bo0 by Molmil
Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer
分子名称: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.2, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
7PFO
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BU of 7pfo by Molmil
Core human replisome
分子名称: Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ...
著者Jones, M.J, Yeeles, J.T.P.
登録日2021-08-11
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of a human replisome shows the organisation and interactions of a DNA replication machine.
Embo J., 40, 2021
6XTX
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CryoEM structure of human CMG bound to ATPgammaS and DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45 homolog, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
著者Rzechorzek, N.J, Pellegrini, L.
登録日2020-01-16
公開日2020-05-27
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020
8B9D
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BU of 8b9d by Molmil
Human replisome bound by Pol Alpha
分子名称: Cell division control protein 45 homolog, Claspin, DNA Molecule, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
5C3I
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BU of 5c3i by Molmil
Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
分子名称: DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ...
著者Wang, H, Wang, M, Yang, N, Xu, R.M.
登録日2015-06-17
公開日2015-07-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Protein Cell, 6, 2015
8YJM
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BU of 8yjm by Molmil
Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera
分子名称: DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2B 1/2/3/4/6,Histone H2A type 1-D, ...
著者Gan, S.L, Yang, W.S, Xu, R.M.
登録日2024-03-02
公開日2024-03-20
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 67, 2024
7W68
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BU of 7w68 by Molmil
human single hexameric Mcm2-7 complex
分子名称: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
著者Xu, N.N, Lin, Q.P, Liu, C.D, Tian, H.L, Xiang, Y, Zhu, G.
登録日2021-12-01
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献human single hexameric Mcm2-7 complex
To Be Published
8YJF
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BU of 8yjf by Molmil
Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and an H2A-H2B dimer
分子名称: DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2A type 1-D, ...
著者Gan, S.L, Yang, W.S, Xu, R.M.
登録日2024-03-01
公開日2024-03-20
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 67, 2024
6XTY
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BU of 6xty by Molmil
CryoEM structure of human CMG bound to AND-1 (CMGA)
分子名称: Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
著者Rzechorzek, N.J, Pellegrini, L, Chirgadze, D.Y, Hardwick, S.W.
登録日2020-01-16
公開日2020-05-27
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.77 Å)
主引用文献CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020

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件を2024-07-10に公開中

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