1MI5
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![BU of 1mi5 by Molmil](/molmil-images/mine/1mi5) | The crystal structure of LC13 TcR in complex with HLAB8-EBV peptide complex | 分子名称: | Epstein Barr Virus peptide, MHC heavy chain, TcR alpha chain, ... | 著者 | Kjer-Nielsen, L, Clements, C.S, Purcell, A.W, Brooks, A.G, Whisstock, J.C, Burrows, S.R, McCluskey, J, Rossjohn, J. | 登録日 | 2002-08-21 | 公開日 | 2003-02-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Structural Basis for the Selection of Dominant alphabeta T Cell Receptors in Antiviral Immunity IMMUNITY, 18, 2003
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5IM7
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![BU of 5im7 by Molmil](/molmil-images/mine/5im7) | |
5VZ5
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![BU of 5vz5 by Molmil](/molmil-images/mine/5vz5) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2017-05-26 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5901 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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6AVG
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![BU of 6avg by Molmil](/molmil-images/mine/6avg) | Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex | 分子名称: | ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gully, B.S, Gras, S, Rossjohn, J. | 登録日 | 2017-09-02 | 公開日 | 2018-02-28 | 最終更新日 | 2018-03-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nat Commun, 9, 2018
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3KPR
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![BU of 3kpr by Molmil](/molmil-images/mine/3kpr) | Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope | 分子名称: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3L3K
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![BU of 3l3k by Molmil](/molmil-images/mine/3l3k) | Crystal structure of HLA-B*4402 in complex with the R5A/F7A double mutant of a self-peptide derived from DPA*0201 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Theodossis, A, Ely, L.K, Rossjohn, J. | 登録日 | 2009-12-17 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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2NX5
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![BU of 2nx5 by Molmil](/molmil-images/mine/2nx5) | Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A | 分子名称: | Beta-2-microglobulin, EBV peptide, EPLPQGQLTAY, ... | 著者 | Tynan, F.E, Reid, H.H, Rossjohn, J. | 登録日 | 2006-11-16 | 公開日 | 2007-02-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule Nat.Immunol., 8, 2007
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3MV9
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![BU of 3mv9 by Molmil](/molmil-images/mine/3mv9) | Crystal Structure of the TK3-Gln55Ala TCR in complex with HLA-B*3501/HPVG | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R. | 登録日 | 2010-05-03 | 公開日 | 2010-06-09 | 最終更新日 | 2011-07-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Allelic polymorphism in the T cell receptor and its impact on immune responses J.Exp.Med., 207, 2010
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1CG9
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![BU of 1cg9 by Molmil](/molmil-images/mine/1cg9) | COMPLEX RECOGNITION OF THE SUPERTYPIC BW6-DETERMINANT ON HLA-B AND-C MOLECULES BY THE MONOCLONAL ANTIBODY SFR8-B6 | 分子名称: | PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (EBNA-6 NUCLEAR PROTEIN (EBNA-3C) (EBNA-4B)), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Menssen, R, Orth, P, Ziegler, A, Saenger, W. | 登録日 | 1999-03-25 | 公開日 | 2003-11-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Complex Recognition of the Supertypic Bw6-Determinant on HLA-B and-C Molecules
by the Monoclonal Antibody SFR8-B6 To be Published
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3KPS
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![BU of 3kps by Molmil](/molmil-images/mine/3kps) | Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLQAFTY a self peptide from the ABCD3 protein | 分子名称: | Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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5XOT
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![BU of 5xot by Molmil](/molmil-images/mine/5xot) | Crystal structure of pHLA-B35 in complex with TU55 T cell receptor | 分子名称: | An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2017-05-31 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.787 Å) | 主引用文献 | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs. J. Virol., 91, 2017
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3FFC
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![BU of 3ffc by Molmil](/molmil-images/mine/3ffc) | Crystal Structure of CF34 TCR in complex with HLA-B8/FLR | 分子名称: | Beta-2-microglobulin, CADMIUM ION, CF34 alpha chain, ... | 著者 | Gras, S, Burrows, S.R, Kjer-Nielsen, L, Clements, C.S, Liu, Y.C, Sullivan, L.C, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J. | 登録日 | 2008-12-03 | 公開日 | 2009-01-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The shaping of T cell receptor recognition by self-tolerance. Immunity, 30, 2009
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5V5M
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![BU of 5v5m by Molmil](/molmil-images/mine/5v5m) | |
7LGD
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![BU of 7lgd by Molmil](/molmil-images/mine/7lgd) | HLA-B*07:02 in complex with SARS-CoV-2 nucleocapsid peptide N105-113 | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Szeto, C, Chatzileontiadou, D.S.M. | 登録日 | 2021-01-20 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses. Immunity, 54, 2021
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5INC
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![BU of 5inc by Molmil](/molmil-images/mine/5inc) | Crystal structure of HLA-B5801, a protective HLA allele for HIV-1 infection | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, HLA class I histocompatibility antigen, ... | 著者 | Li, X, Wang, J.-H. | 登録日 | 2016-03-07 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.881 Å) | 主引用文献 | Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection. Protein Cell, 7, 2016
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4QRP
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![BU of 4qrp by Molmil](/molmil-images/mine/4qrp) | Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR | 分子名称: | Beta-2-microglobulin, DD31 TCR alpha chain, DD31 TCR beta chain, ... | 著者 | Gras, S, Berry, R, Lucet, I.S, Rossjohn, J. | 登録日 | 2014-07-02 | 公開日 | 2014-11-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant. J.Immunol., 193, 2014
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6UJ9
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![BU of 6uj9 by Molmil](/molmil-images/mine/6uj9) | Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide in complex with Fab | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Thirawatananond, P, Aytenfisu, T.Y, Wright, K, Gabelli, S.B. | 登録日 | 2019-10-02 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun, 12, 2021
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4MJI
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![BU of 4mji by Molmil](/molmil-images/mine/4mji) | T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01 | 分子名称: | Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M. | 登録日 | 2013-09-03 | 公開日 | 2014-05-28 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01 J.Immunol., 192, 2014
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4QRR
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![BU of 4qrr by Molmil](/molmil-images/mine/4qrr) | Crystal Structure of HLA B*3501-IPS in complex with a Delta-Beta TCR, clone 12 TCR | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Gras, S, Chabrol, E, Rossjohn, J. | 登録日 | 2014-07-02 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The molecular bases of delta / alpha beta T cell-mediated antigen recognition. J.Exp.Med., 211, 2014
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6MTM
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![BU of 6mtm by Molmil](/molmil-images/mine/6mtm) | |
1E28
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![BU of 1e28 by Molmil](/molmil-images/mine/1e28) | Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM2(TAFTIPSI) | 分子名称: | BETA-2 MICROGLOBULIN LIGHT CHAIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HEAVY CHAIN, PEPTIDE | 著者 | Maenaka, K, Maenaka, T, Tomiyama, H, Takiguchi, M, Stuart, D.I, Jones, E.Y. | 登録日 | 2000-05-18 | 公開日 | 2000-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes. J Immunol., 165, 2000
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3SJV
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![BU of 3sjv by Molmil](/molmil-images/mine/3sjv) | Crystal structure of the RL42 TCR in complex with HLA-B8-FLR | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | 登録日 | 2011-06-22 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188, 2012
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6VMX
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![BU of 6vmx by Molmil](/molmil-images/mine/6vmx) | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Farenc, C, Rossjohn, J, Gras, S. | 登録日 | 2020-01-28 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals. J Immunol., 205, 2020
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3KXF
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![BU of 3kxf by Molmil](/molmil-images/mine/3kxf) | Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J. | 登録日 | 2009-12-03 | 公開日 | 2010-06-09 | 最終更新日 | 2014-02-26 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability Proc.Natl.Acad.Sci.USA, 107, 2010
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3W39
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![BU of 3w39 by Molmil](/molmil-images/mine/3w39) | Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-52 alpha chain, ... | 著者 | Yagita, Y, Kuse, N, Kuroki, K, Gatanaga, H, Carlson, J.M, Chikata, T, Brumme, Z.L, Murakoshi, H, Akahoshi, T, Pfeifer, N, Mallal, S, John, M, Ose, T, Matsubara, H, Kanda, R, Fukunaga, Y, Honda, K, Kawashima, Y, Ariumi, Y, Oka, S, Maenaka, K, Takiguchi, M. | 登録日 | 2012-12-13 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity J.Virol., 87, 2013
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