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6UJ9

Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide in complex with Fab

Summary for 6UJ9
Entry DOI10.2210/pdb6uj9/pdb
DescriptorHLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, Isocitrate dehydrogenase [NADP], mitochondrial, ... (9 entities in total)
Functional Keywordshla-b7, mhc-i, immunotherapy, idh2, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains5
Total formula weight97767.39
Authors
Miller, M.S.,Thirawatananond, P.,Aytenfisu, T.Y.,Wright, K.,Gabelli, S.B. (deposition date: 2019-10-02, release date: 2021-05-05, Last modification date: 2023-10-11)
Primary citationHwang, M.S.,Miller, M.S.,Thirawatananond, P.,Douglass, J.,Wright, K.M.,Hsiue, E.H.,Mog, B.J.,Aytenfisu, T.Y.,Murphy, M.B.,Aitana Azurmendi, P.,Skora, A.D.,Pearlman, A.H.,Paul, S.,DiNapoli, S.R.,Konig, M.F.,Bettegowda, C.,Pardoll, D.M.,Papadopoulos, N.,Kinzler, K.W.,Vogelstein, B.,Zhou, S.,Gabelli, S.B.
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12:5271-5271, 2021
Cited by
PubMed: 34489470
DOI: 10.1038/s41467-021-25605-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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